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http://hdl.handle.net/2445/188980
Title: | SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV |
Author: | Nomah, Daniel Kwakye Llibre, Josep Maria Díaz, Yesika Moreno, Sergio Aceiton, Jordi Bruguera, Andreu Gutiérrez Macià, Maria Imaz, Arkaitz Suanzes, Paula Navarro, Gemma Orti, Amat Miró Meda, José M. Casabona, Jordi Reyes Urueña, Juliana The Piscis Study Group |
Keywords: | COVID-19 Vacunació COVID-19 Vaccination |
Issue Date: | 18-Aug-2022 |
Publisher: | MDPI AG |
Abstract: | People living with HIV (PLWH) are prioritised for SARS-CoV-2 vaccination due to their vulnerability to severe COVID-19. Therefore, the epidemiological surveillance of vaccination coverage and the timely identification of suboptimally vaccinated PLWH is vital. We assessed SARS-CoV-2 vaccination coverage and factors associated with under-vaccination among PLWH in Catalonia, Spain. As of 11.12.2021, 9945/14942 PLWH (66.6%) had received >= 1 dose of a SARS-CoV-2 vaccine. Non-Spanish origin (adjusted odds ratio (aOR) 0.64, 95% CI 0.59-0.70), CD4 count of 200-349 cells/mu L (aOR 0.74, 95% CI 0.64-0.86) or 350-499 cells/mu L (aOR 0.79, 95% CI 0.70-0.88), detectable plasma HIV-RNA (aOR 0.61 95% CI 0.53-0.70), and previous SARS-CoV-2 diagnosis (aOR 0.58 95% CI 0.51-0.65) were associated with under-vaccination. SARS-CoV-2 diagnosis (437 [9.5%] vs. 323 [3.5%], p < 0.001), associated hospitalisations (10 [2.3%] vs. 0 [0%], p < 0.001), intensive care unit admissions (6 [1.4%] vs. 0 [0%], p < 0.001), and deaths (10 [2.3%] vs. 0 [0%], p < 0.001) were higher among unvaccinated PLWH. Vaccination coverage was lower among PLWH with a CD4 count >200 cells/mu L, detectable plasma HIV-RNA, previous SARS-CoV-2 diagnosis, and migrants. SARS-CoV-2 diagnosis, associated hospitalisations, and deaths among PLWH were lower among the vaccinated compared with the unvaccinated. SARS-CoV-2 vaccination prioritisation has not completely reached vulnerable PLWH with poorer prognosis. This information can be used to inform public health strategies. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/microorganisms10081666 |
It is part of: | Microorganisms, 2022 |
URI: | http://hdl.handle.net/2445/188980 |
Related resource: | https://doi.org/10.3390/microorganisms10081666 |
ISSN: | 2076-2607 |
Appears in Collections: | Articles publicats en revistes (Medicina) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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