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http://hdl.handle.net/2445/189305| Title: | ERK-mediated mechanochemical waves direct collective cell polarization |
| Author: | Hino, Naoya Rossetti, Leone Marín Llaurado, Ariadna Aoki, Kazuhiro Trepat Guixer, Xavier Matsuda, Michiyuki Hirashima, Tsuyoshi |
| Keywords: | Bioquímica Biomecànica Biochemistry Biomechanics |
| Issue Date: | 22-Jun-2020 |
| Abstract: | During collective cell migration, directional information is transmitted from a leading edge to the follower cells as a form of ERK activation waves. Hino et al. demonstrate that a mechanochemical feedback loop coupling cell deformation and ERK activation enables sustained propagation of the directional information over a tissue-scale expanse. |
| Note: | Reproducció del document publicat a: https://doi.org/10.1016/j.devcel.2020.05.011 |
| It is part of: | Developmental Cell, 2020, vol. 53, num. 6 |
| URI: | http://hdl.handle.net/2445/189305 |
| Related resource: | https://doi.org/10.1016/j.devcel.2020.05.011 |
| ISSN: | 1878-1551 |
| Appears in Collections: | Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC)) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2020_DevCel_ERK_HirashimaT_preprint.pdf | 11.11 MB | Adobe PDF | View/Open |
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