Please use this identifier to cite or link to this item:
Title: Clinical and functional characteristics of patients two years after being affected by the soybean asthma epidemic in Barcelona
Author: Sabrià, Josefina
Antó, Josep M.
Sunyer, Jordi
Roca, Josep
Morell, Ferran
Rodríguez-Roisin, Robert
Rodrigo, María J.
Codina, Rosa
Keywords: Asma
Barcelona (Catalunya : Àrea metropolitana)
Barcelona (Catalonia : Metropolitan area)
Issue Date: 1994
Publisher: BMJ Publishing Group
Abstract: Background: Patients affected during the asthma outbreaks caused by soybean dust inhalation in Barcelona presented with sudden onset of severe asthma followed by the rapid relief of symptoms after treatment. Two years after the epidemics ended, a case-control study was conducted in which the clinical, functional, and immunological characteristics of these asthma patients (a randomised sample of asthmatic patients admitted as emergency cases on epidemic days, n = 213) were compared with those of a control group (a random sample of asthmatic patients admitted as emergency cases for attacks of asthma on non-epidemic days, n = 170). METHODS--The study included the administration of the ATS-DLD78 standardised respiratory questionnaire, the measurement of atopy, and performance of spirometric tests and a methacholine inhalation test. Results: Patients with epidemic asthma reported fewer symptoms of asthma, had attended emergency departments less frequently during the previous year for acute attacks of asthma, were taking fewer inhaled corticosteroids at the time of the study, and attended medical follow up less frequently than did the patients with non-epidemic asthma. However, the cases and controls showed no differences in ventilatory capacity or reactivity to the methacholine bronchoprovocation test. Conclusions: Two years after the end of the soybean epidemics, people affected by epidemic asthma had a favourable prognosis. This finding contrasts with a higher risk of life threatening asthma and death during the epidemics. This paradox could be the result of a complex interaction between host and conditions of exposure.
Note: Reproducció del document publicat a:
It is part of: Thorax, 1994, vol. 49, p. 906-909
Related resource:
ISSN: 0040-6376
Appears in Collections:Articles publicats en revistes (Medicina)

Files in This Item:
File Description SizeFormat 
097499.pdf905.16 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.