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http://hdl.handle.net/2445/189350
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DC Field | Value | Language |
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dc.contributor.author | Vilchez, Helem H. | - |
dc.contributor.author | Escudero Sánchez, Rosa | - |
dc.contributor.author | Fernandez-Sampedro, Marta | - |
dc.contributor.author | Murillo Rubio, Óscar | - |
dc.contributor.author | Auñón, Álvaro | - |
dc.contributor.author | Rodríguez-Pardo, Dolors | - |
dc.contributor.author | Jover-Sáenz, Alfredo | - |
dc.contributor.author | Del Toro, Maria Dolores | - |
dc.contributor.author | Rico, Alicia | - |
dc.contributor.author | Falgueras, Luis | - |
dc.contributor.author | Praena Segovia, Julia | - |
dc.contributor.author | Guío, Laura | - |
dc.contributor.author | Iribarren, José A. | - |
dc.contributor.author | Lora-Tamayo Morillo-Velarde, Jaime | - |
dc.contributor.author | Benito Hernández, M. Natividad de | - |
dc.contributor.author | Morata, Laura | - |
dc.contributor.author | Ramirez, Antonio | - |
dc.contributor.author | Riera, Melchor | - |
dc.date.accessioned | 2022-09-27T17:24:52Z | - |
dc.date.available | 2022-09-27T17:24:52Z | - |
dc.date.issued | 2021-04-21 | - |
dc.identifier.issn | 2079-6382 | - |
dc.identifier.uri | http://hdl.handle.net/2445/189350 | - |
dc.description.abstract | This retrospective, multicenter observational study aimed to describe the outcomes of surgical and medical treatment of C. acnes-related prosthetic joint infection (PJI) and the potential benefit of rifampin-based therapies. Patients with C. acnes-related PJI who were diagnosed and treated between January 2003 and December 2016 were included. We analyzed 44 patients with C. acnes-related PJI (median age, 67.5 years (IQR, 57.3-75.8)); 75% were men. The majority (61.4%) had late chronic infection according to the Tsukayama classification. All patients received surgical treatment, and most antibiotic regimens (43.2%) included β-lactam. Thirty-four patients (87.17%) were cured; five showed relapse. The final outcome (cure vs. relapse) showed a nonsignificant trend toward higher failure frequency among patients with previous prosthesis (OR: 6.89; 95% CI: 0.80-58.90) or prior surgery and infection (OR: 10.67; 95% IC: 1.08-105.28) in the same joint. Patients treated with clindamycin alone had a higher recurrence rate (40.0% vs. 8.8%). Rifampin treatment did not decrease recurrence in patients treated with β-lactams. Prior prosthesis, surgery, or infection in the same joint might be related to recurrence, and rifampin-based combinations do not seem to improve prognosis. Debridement and implant retention appear a safe option for surgical treatment of early PJI. | - |
dc.format.extent | 13 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/antibiotics10050475 | - |
dc.relation.ispartof | Antibiotics, 2021, vol. 10, num. 5 | - |
dc.relation.uri | https://doi.org/10.3390/antibiotics10050475 | - |
dc.rights | cc-by (c) Vilchez, Helem H. et al., 2021 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Bacteris anaerobis | - |
dc.subject.classification | Infeccions | - |
dc.subject.classification | Cirurgia | - |
dc.subject.classification | Pròtesis | - |
dc.subject.other | Anaerobic bacteria | - |
dc.subject.other | Infections | - |
dc.subject.other | Surgery | - |
dc.subject.other | Prosthesis | - |
dc.title | Prosthetic shoulder joint infection by Cutibacterium acnes: does rifampin improve prognosis? a retrospective, multicenter, observational study. | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 720015 | - |
dc.date.updated | 2022-09-27T17:24:52Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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720015.pdf | 612.71 kB | Adobe PDF | View/Open |
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