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dc.contributor.authorVilchez, Helem H.-
dc.contributor.authorEscudero Sánchez, Rosa-
dc.contributor.authorFernandez-Sampedro, Marta-
dc.contributor.authorMurillo Rubio, Óscar-
dc.contributor.authorAuñón, Álvaro-
dc.contributor.authorRodríguez-Pardo, Dolors-
dc.contributor.authorJover-Sáenz, Alfredo-
dc.contributor.authorDel Toro, Maria Dolores-
dc.contributor.authorRico, Alicia-
dc.contributor.authorFalgueras, Luis-
dc.contributor.authorPraena Segovia, Julia-
dc.contributor.authorGuío, Laura-
dc.contributor.authorIribarren, José A.-
dc.contributor.authorLora-Tamayo Morillo-Velarde, Jaime-
dc.contributor.authorBenito Hernández, M. Natividad de-
dc.contributor.authorMorata, Laura-
dc.contributor.authorRamirez, Antonio-
dc.contributor.authorRiera, Melchor-
dc.description.abstractThis retrospective, multicenter observational study aimed to describe the outcomes of surgical and medical treatment of C. acnes-related prosthetic joint infection (PJI) and the potential benefit of rifampin-based therapies. Patients with C. acnes-related PJI who were diagnosed and treated between January 2003 and December 2016 were included. We analyzed 44 patients with C. acnes-related PJI (median age, 67.5 years (IQR, 57.3-75.8)); 75% were men. The majority (61.4%) had late chronic infection according to the Tsukayama classification. All patients received surgical treatment, and most antibiotic regimens (43.2%) included β-lactam. Thirty-four patients (87.17%) were cured; five showed relapse. The final outcome (cure vs. relapse) showed a nonsignificant trend toward higher failure frequency among patients with previous prosthesis (OR: 6.89; 95% CI: 0.80-58.90) or prior surgery and infection (OR: 10.67; 95% IC: 1.08-105.28) in the same joint. Patients treated with clindamycin alone had a higher recurrence rate (40.0% vs. 8.8%). Rifampin treatment did not decrease recurrence in patients treated with β-lactams. Prior prosthesis, surgery, or infection in the same joint might be related to recurrence, and rifampin-based combinations do not seem to improve prognosis. Debridement and implant retention appear a safe option for surgical treatment of early PJI.-
dc.format.extent13 p.-
dc.relation.isformatofReproducció del document publicat a:
dc.relation.ispartofAntibiotics, 2021, vol. 10, num. 5-
dc.rightscc-by (c) Vilchez, Helem H. et al., 2021-
dc.sourceArticles publicats en revistes (Ciències Clíniques)-
dc.subject.classificationBacteris anaerobis-
dc.subject.otherAnaerobic bacteria-
dc.titleProsthetic shoulder joint infection by Cutibacterium acnes: does rifampin improve prognosis? a retrospective, multicenter, observational study.-
Appears in Collections:Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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