Please use this identifier to cite or link to this item:
https://hdl.handle.net/2445/190194
Title: | COLONOMICS - integrative omics data of one hundred paired normal-tumoral samples from colon cancer patients |
Author: | Díez Villanueva, Anna Sanz Pamplona, Rebeca Solé, Xevi Cordero, David Crous Bou, Marta Guinó, Elisabet López Dóriga Guerra, Adriana Berenguer, Antoni Aussó, Susanna Paré, Laia Obón Santacana, Mireia Moratalla Navarro, Ferran Salazar Soler, Ramón Sanjuan, Xavier Santos, Cristina Biondo, Sebastián Diez Obrero, Virginia Garcia Serrano, Ainhoa Alonso Aguado, Maria Henar Carreras Torres, Robert Closa, Adria Moreno Aguado, Víctor |
Keywords: | Còlon Micro RNAs Colon MicroRNAs |
Issue Date: | 1-Oct-2022 |
Publisher: | Springer Science and Business Media LLC |
Abstract: | Colonomics is a multi-omics dataset that includes 250 samples: 50 samples from healthy colon mucosa donors and 100 paired samples from colon cancer patients (tumor/adjacent). From these samples, Colonomics project includes data from genotyping, DNA methylation, gene expression, whole exome sequencing and micro-RNAs (miRNAs) expression. It also includes data from copy number variation (CNV) from tumoral samples. In addition, clinical data from all these samples is available. The aims of the project were to explore and integrate these datasets to describe colon cancer at molecular level and to compare normal and tumoral tissues. Also, to improve screening by finding biomarkers for the diagnosis and prognosis of colon cancer. This project has its own website including four browsers allowing users to explore Colonomics datasets. Since generated data could be reuse for the scientific community for exploratory or validation purposes, here we describe omics datasets included in the Colonomics project as well as results from multi-omics layers integration. |
Note: | Reproducció del document publicat a: https://doi.org/10.1038/s41597-022-01697-5 |
It is part of: | Scientific Data, 2022, vol. 9, issue. 1 |
URI: | https://hdl.handle.net/2445/190194 |
Related resource: | https://doi.org/10.1038/s41597-022-01697-5 https://doi.org/10.1038/s41597-022-01829-x |
ISSN: | 2052-4463 |
Appears in Collections: | Articles publicats en revistes (Institut de Recerca en Sistemes Complexos (UBICS)) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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s41597-022-01697-5.pdf | Original Article | 1.12 MB | Adobe PDF | View/Open |
s41597-022-01829-x.pdf | Author Correction | 620.99 kB | Adobe PDF | View/Open |
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