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http://hdl.handle.net/2445/190795
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DC Field | Value | Language |
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dc.contributor.author | Formiga Pérez, Francesc | - |
dc.contributor.author | Chivite, David | - |
dc.contributor.author | Nuñez, Julio | - |
dc.contributor.author | Moreno García, Ma. Carmen | - |
dc.contributor.author | Manzano, Luis | - |
dc.contributor.author | Arévalo-Lorido, José Carlos | - |
dc.contributor.author | Cerqueiro, Jose Manuel | - |
dc.contributor.author | García Campos, Álvaro | - |
dc.contributor.author | Trullàs, Joan Carles | - |
dc.contributor.author | Montero Pérez-Barquero, Manuel | - |
dc.date.accessioned | 2022-11-14T18:55:55Z | - |
dc.date.available | 2022-11-14T18:55:55Z | - |
dc.date.issued | 2022-10-01 | - |
dc.identifier.issn | 0870-2551 | - |
dc.identifier.uri | http://hdl.handle.net/2445/190795 | - |
dc.description.abstract | Introduction: Beta-adrenergic receptor blockers (beta-blockers) are frequently used for patients with heart failure (HF) with preserved ejection fraction (HFpEF), although evidence-based recommendations for this indication are still lacking. Our goal was to assess which clinical factors are associated with the prescription of beta-blockers in patients discharged after an episode of HFpEF decompensation, and the clinical outcomes of these patients. Methods: We assessed 1078 patients with HFpEF and in sinus rhythm who had experienced an acute HF episode to explore whether prescription of beta-blockers on discharge was associated with one-year all-cause mortality or the composite endpoint of one-year all-cause death or HF readmission. We also examined the clinical factors associated with beta-blocker discharge prescription for such patients. Results: At discharge, 531 (49.3%) patients were on beta-blocker therapy. Patients on beta-blockers more often had a prior diagnosis of hypertension and more comorbidity (including ischemic heart disease) and a better functional status, but less often a prior diagnosis of chronic obstructive pulmonary disease. These patients had a lower heart rate on admission and more often used angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, angiotensin receptor-neprilysin inhibitors and loop diuretics. One year after the index admission, 161 patients (15%) had died and 314 (29%) had experienced the composite endpoint. After multivariate adjustment, beta-blocker prescription was not associated with either all-cause mortality (HR=0.83 [95% CI 0.61-1.13]; p=0.236) or the composite endpoint (HR=0.98 [95% CI 0.79-1.23]; p=0.882). Conclusion: In patients with HFpEF in sinus rhythm, beta-blocker use was not related to one-year mortality or mortality plus HF readmission. | - |
dc.format.extent | 9 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier España | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1016/j.repc.2021.06.027 | - |
dc.relation.ispartof | Revista Portuguesa de Cardiologia, 2022, vol. 41, num. 10, p. 853-861 | - |
dc.relation.uri | https://doi.org/10.1016/j.repc.2021.06.027 | - |
dc.rights | cc-by-nc-nd (c) Sociedade Portuguesa de Cardiologia , 2022 | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Angiotensines | - |
dc.subject.classification | Arrítmia | - |
dc.subject.classification | Mortalitat | - |
dc.subject.classification | Insuficiència cardíaca | - |
dc.subject.other | Angiotensins | - |
dc.subject.other | Arrhythmia | - |
dc.subject.other | Mortality | - |
dc.subject.other | Heart failure | - |
dc.title | Beta-blocker use in patients with heart failure with preserved ejection fraction and sinus rhythm | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 725589 | - |
dc.date.updated | 2022-11-14T18:55:55Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 36207068 | - |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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725589.pdf | 737.67 kB | Adobe PDF | View/Open |
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