1. Dipòsit Digital de la Universitat de Barcelona
  2. Recerca
  3. Farmacologia, Toxicologia i Química Terapèutica
  4. Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/191606
Full metadata record
DC FieldValueLanguage
dc.contributor.authorFernandez, Antonio-
dc.contributor.authorKielland, Nicola-
dc.contributor.authorMakda, Ashraff-
dc.contributor.authorCarragher, Neil-
dc.contributor.authorGonzález-García, M. Carmen-
dc.contributor.authorEspinar-Barranco, Laura-
dc.contributor.authorGonzález-Vera, Juan Antonio-
dc.contributor.authorOrte, Ángel-
dc.contributor.authorLavilla Grífols, Rodolfo-
dc.contributor.authorVendrell, Marc-
dc.date.accessioned2022-12-15T12:12:04Z-
dc.date.available2022-12-15T12:12:04Z-
dc.date.issued2022-08-28-
dc.identifier.issn2227-9059-
dc.identifier.urihttp://hdl.handle.net/2445/191606-
dc.description.abstractWe report a platform combining multicomponent reaction synthesis and automated cell-based screening to develop biocompatible NIR-BODIPY fluorophores. From a library of over 60 fluorophores, we optimised compound NIRBD-62c as a multimodal probe with suitable properties for STED super-resolution and fluorescence lifetime imaging. Furthermore, we employed NIRBD-62c for imaging trafficking inside cells and to examine how pharmacological inhibitors can alter the vesicular traffic between intracellular compartments and the plasma membrane.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherMDPI-
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1039/d2cb00168c-
dc.relation.ispartofBiomedicines, 2022-
dc.relation.urihttps://doi.org/10.1039/d2cb00168c-
dc.rightscc-by (c) Fernandez, Antonio et al., 2022-
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/-
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)-
dc.subject.classificationQuímica farmacèutica-
dc.subject.classificationSíntesi orgànica-
dc.subject.otherPharmaceutical chemistry-
dc.subject.otherOrganic synthesis-
dc.titleA multicomponent reaction platform towards multimodal near-infrared BODIPY dyes for STED and fluorescence lifetime imaging-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.identifier.idgrec724484-
dc.date.updated2022-12-15T12:12:04Z-
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/771443/EU//DYNAFLUORS-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
Appears in Collections:Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

Files in This Item:
File Description SizeFormat 
724484.pdf2.93 MBAdobe PDFView/Open
Show simple item record


This item is licensed under a Creative Commons License Creative Commons