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http://hdl.handle.net/2445/191974
Title: | Isavuconazole prophylaxis against invasive fungal infections in allogeneic stem cell transplantation: a single-center experience |
Author: | Queralt Salas, Maria Mussetti, Alberto Muñóz, Carme Albasanz Puig, Adaia Patiño, Beatriz Jimenez Prat, Laura Gudiol González, Carlota Parody, Rocío Sureda, Anna |
Keywords: | Cèl·lules mare Medicaments antifúngics Medicina preventiva Stem cells Antifungal agents Preventive medicine |
Issue Date: | 8-Feb-2021 |
Publisher: | Elsevier |
Abstract: | Patients undergoing allogeneic stem cell transplantation (alloHCT) require profound immunosuppression is required to preserve graft function and prevent graft-versus host disease (GVHD), resulting in a high risk of infectious complications such as invasive fungal diseases (IFIs). Posaconazole is approved for primary antifungal prophylaxis alloHCT. However, posaconazole is associated with drug-drug interactions which may lead to relevant toxicities limiting it uses in hematological patients. Other triazoles, amphotericine B, and echinocandins can be used in patients at high risk of IFIs. However, there is less evidence supporting the efficacy of these drugs for the prevention of IFIs. |
Note: | Reproducció del document publicat a: https://doi.org/10.1016/j.htct.2021.01.002 |
It is part of: | Hematology, Transfusion and Cell Therapy, 2021, vol. 44, num. 3, p. 440-443 |
URI: | http://hdl.handle.net/2445/191974 |
Related resource: | https://doi.org/10.1016/j.htct.2021.01.002 |
ISSN: | 2531-1379 |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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