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DC Field | Value | Language |
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dc.contributor.author | Valle-Hita, Cristina | - |
dc.contributor.author | Becerra Tomás, Nerea | - |
dc.contributor.author | Díaz López, Andrés | - |
dc.contributor.author | Vázquez Ruiz, Zenaida | - |
dc.contributor.author | Megías, Isabel | - |
dc.contributor.author | Corella Piquer, Dolores | - |
dc.contributor.author | Goday Arnó, Albert | - |
dc.contributor.author | Martínez, J. Alfredo, 1957- | - |
dc.contributor.author | Alonso Gómez, Ángel M. | - |
dc.contributor.author | Wärnberg, Julia | - |
dc.contributor.author | Vioque, Jesús | - |
dc.contributor.author | Romaguera, Dora | - |
dc.contributor.author | López Miranda, José | - |
dc.contributor.author | Estruch Riba, Ramon | - |
dc.contributor.author | Tinahones, Francisco J. | - |
dc.contributor.author | Lapetra, José | - |
dc.contributor.author | Serra Majem, Lluís | - |
dc.contributor.author | Bueno-Cavanillas, Aurora | - |
dc.contributor.author | Tur, Josep Antoni | - |
dc.contributor.author | Martín-Sánchez, Vicente | - |
dc.contributor.author | Pintó Sala, Xavier | - |
dc.contributor.author | Gaforio, José J. | - |
dc.contributor.author | Matía Martín, Pilar | - |
dc.contributor.author | Vidal i Cortada, Josep | - |
dc.contributor.author | Amengual-Galbarte, Angela | - |
dc.contributor.author | Daimiel, Lidia | - |
dc.contributor.author | Ros Rahola, Emilio | - |
dc.contributor.author | Garcia-Arellano, Ana | - |
dc.contributor.author | Barragán, Rocío | - |
dc.contributor.author | Fitó Colomer, Montserrat | - |
dc.contributor.author | Peña Orihuela, Patricia J. | - |
dc.contributor.author | Asencio, Alberto | - |
dc.contributor.author | Gómez Gracia, Enrique | - |
dc.contributor.author | Martinez Urbistondo, Diego | - |
dc.contributor.author | Morey, Marga | - |
dc.contributor.author | Casas, Rosa | - |
dc.contributor.author | Garrido-Garrido, Eva Maria | - |
dc.contributor.author | Tojal Sierra, Lucas | - |
dc.contributor.author | Damas-Fuentes, Miguel | - |
dc.contributor.author | Goñi, Estibaliz | - |
dc.contributor.author | Ortega Azorín, Carolina | - |
dc.contributor.author | Castañer, Olga | - |
dc.contributor.author | Garcia-Rios, Antonio | - |
dc.contributor.author | Gisbert Sellés, Cristina | - |
dc.contributor.author | Sayón Orea, Carmen | - |
dc.contributor.author | Schröder, Helmut, 1958- | - |
dc.contributor.author | Salas Salvadó, Jordi | - |
dc.contributor.author | Babio, Nancy | - |
dc.date.accessioned | 2023-01-17T19:20:31Z | - |
dc.date.available | 2023-01-17T19:20:31Z | - |
dc.date.issued | 2022-09-30 | - |
dc.identifier.issn | 2296-861X | - |
dc.identifier.uri | http://hdl.handle.net/2445/192271 | - |
dc.description.abstract | Background: Diets high in acid load may contribute to kidney function impairment. This study aimed to investigate the association between dietary acid load and 1-year changes in glomerular filtration rate (eGFR) and urine albumin/creatinine ratio (UACR). Methods: Older adults with overweight/obesity and metabolic syndrome (mean age 65 ± 5 years, 48% women) from the PREDIMED-Plus study who had available data on eGFR (n = 5,874) or UACR (n = 3,639) at baseline and after 1 year of follow-up were included in this prospective analysis. Dietary acid load was estimated as potential renal acid load (PRAL) and net endogenous acid production (NEAP) at baseline from a food frequency questionnaire. Linear and logistic regression models were fitted to evaluate the associations between baseline tertiles of dietary acid load and kidney function outcomes. One year-changes in eGFR and UACR were set as the primary outcomes. We secondarily assessed ≥ 10% eGFR decline or ≥10% UACR increase. Results: After multiple adjustments, individuals in the highest tertile of PRAL or NEAP showed higher one-year changes in eGFR (PRAL, β: -0.64 ml/min/1.73 m2; 95% CI: -1.21 to -0.08 and NEAP, β: -0.56 ml/min/1.73 m2; 95% CI: -1.13 to 0.01) compared to those in the lowest category. No associations with changes in UACR were found. Participants with higher levels of PRAL and NEAP had significantly higher odds of developing ≥10% eGFR decline (PRAL, OR: 1.28; 95% CI: 1.07-1.54 and NEAP, OR: 1.24; 95% CI: 1.03-1.50) and ≥10 % UACR increase (PRAL, OR: 1.23; 95% CI: 1.04-1.46) compared to individuals with lower dietary acid load. Conclusions: Higher PRAL and NEAP were associated with worse kidney function after 1 year of follow-up as measured by eGFR and UACR markers in an older Spanish population with overweight/obesity and metabolic syndrome. Keywords: albuminuria; chronic kidney disease (CKD); dietary acid load; glomerular filtration rate (GFR); kidney function; net endogenous acid production (NEAP); potential renal acid load (PRAL); renal nutrition. | - |
dc.format.extent | 13 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Frontiers Media | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3389/fnut.2022.986190 | - |
dc.relation.ispartof | Frontiers In Nutrition, 2022, vol. 9, p. 986190 | - |
dc.relation.uri | https://doi.org/10.3389/fnut.2022.986190 | - |
dc.rights | cc-by (c) Valle-Hita, Cristina et al., 2022 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Malalties del ronyó | - |
dc.subject.classification | Síndrome metabòlica | - |
dc.subject.classification | Nutrició | - |
dc.subject.other | Kidney diseases | - |
dc.subject.other | Metabolic syndrome | - |
dc.subject.other | Nutrition | - |
dc.title | Longitudinal association of dietary acid load with kidney function decline in an older adult population with metabolic syndrome | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 725925 | - |
dc.date.updated | 2023-01-17T19:20:31Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.idimarina | 9331349 | - |
dc.identifier.pmid | 36245494 | - |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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