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Title: Incidence of mandibular osteoradionecrosis (MORN) after intensity modulated radiotherapy (IMRT) versus 3D conformal radiotherapy (3D-CRT): A systematic review
Author: Céspedes Ajún, Carlos Arturo
Amghar Maach, Sara
Gay Escoda, Cosme
Keywords: Radioteràpia
Issue Date: 1-Jan-2022
Publisher: Medicina Oral, S.L.
Abstract: Background: Analyze the incidence of MORN after head and neck radiotherapy by two novel irradiation techniques. 3DCRT and IMRT and compare the success rates of distinct authors. Material and Methods: An electronic search in Pubmed (MEDLINE), Ovid. Google Scholar and Cochrane Library (Wiley). databases was conducted with the key words Radiotherapy, Conformal[Mesh] OR Radiotherapy. Intensity-Modulated[Mesh]) AND Osteoradionecrosis[Mesh] for all databases. The inclusion criteria randomized controlled trials (RCT), as well as prospective and retrospective cohort studies published in English; MORN patients treated with 3D-CRT y IMRT. Results: 27 articles were selected from 194 initially found. 14 articles out of 27 were excluded and finally included 8 publications were included in the systematic review that were ranked according to their level of scientific evidence using the SORT criteria. Conclusions: When both RT techniques were compared; IMRT revealed a lower risk incidence of MORN development and enhanced dose constraint than 3D-CRT (less than 10%). this improvement could translate into less complications post RT treatment.
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It is part of: Medicina Oral Patología Oral y Cirugia Bucal, 2022, vol. 27, num. 6, p. e539-e549
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ISSN: 1698-4447
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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