Please use this identifier to cite or link to this item:
Title: Factors associated with the clinical outcome of patients with relapsed/refractory CD19+acute lymphoblastic leukemia treated with ARI-0001 CART19-cell therapy
Author: Ortiz-Maldonado, Valentín
Rives, Susana
Español Rego, Marta
Alonso Saladrigues, A.
Montoro, Mercedes
Magnano, Laura
Giné Soca, Eva
Pascal i Capdevila, Mariona
Díaz Beyà, Marina
Castella, Maria
Català, Albert
Faura, Anna
Rodríguez Lobato, Luis Gerardo
Oliver Caldés, Aina
Martínez Roca, Alexandra
Rovira, Montserrat
González Navarro, Europa Azucena
Ortega, Juan Ramón
Cid Vidal, Joan
Lozano, Miquel
García Rey, Enric
Fernández, Sara
Castro Rebollo, Pedro
Jordán García, Iolanda
Villamor i Casas, Neus
Aymerich Gregorio, Marta
Torrebadell, Montserrat
Deyá, Angela
Fernández de Larrea Rodríguez, Carlos José
Benítez-Ribas, Daniel
Trias, Esteve
Varea, Sara
Calvo Rojas, Gonzalo
Esteve, Jordi
Urbano Ispizua, Álvaro
Juan, Manel
Delgado, Julio (Delgado González)
Keywords: Leucèmia limfocítica crònica
Cèl·lules canceroses
Teràpia cel·lular
Antígens CD
Receptors cel·lulars
Chronic lymphocytic leukemia
Cancer cells
Cellular therapy
CD antigens
Cell receptors
Issue Date: 1-Dec-2021
Publisher: BMJ Publishing Group
Abstract: The prognosis of patients with relapsed/refractory (R/R) acute lymphoblastic leukemia (ALL) remains poor, particularly for those relapsing after allogeneic hema-topoietic cell transplantation (alloHCT). Novel agents such as inotuzumab ozogamicin or blinatumomab achieve increased response rates, but these are generally transient unless followed by alloHCT. Chimeric antigen receptors (CAR) targeting CD19 have shown promising results in R/R ALL, and one of these products (tisagenlecleucel) has been approved for the treatment of patients with R/R ALL up to 25 years of age.
Note: Reproducció del document publicat a:
It is part of: Journal for ImmunoTherapy of Cancer , 2021, vol. 9, num. 12, p. e003644
Related resource:
ISSN: 2051-1426
Appears in Collections:Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Files in This Item:
File Description SizeFormat 
718809.pdf571.93 kBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons