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Title: | Sleep and breast and prostate cancer risk in the MCC-Spain study |
Author: | Turner, Michelle C. Gracia Lavedan, Esther Papantoniou, Kyriaki Aragonés, Nuria Castaño Vinyals, Gemma Dierssen Sotos, Trinidad Amiano, Pilar Ardanaz, Eva Marcos Delgado, Alba Molina Barceló, Ana Alguacil, Juan Benavente, Yolanda Belmonte, Thalia Jiménez Moleón, José Juan Marcos Gragera, Rafael Pérez, Beatriz Gómez Acebo, Inés Pollán, Marina Kogevinas, Manolis |
Keywords: | Càncer de mama Càncer de pròstata Factors de risc en les malalties Son Breast cancer Prostate cancer Risk factors in diseases Sleep |
Issue Date: | 16-Dec-2022 |
Publisher: | Springer Science and Business Media LLC |
Abstract: | Breast and prostate cancers have been associated with circadian disruption. Some previous studies examined associations of sleep duration and breast or prostate cancer risk though findings remain inconsistent. This study examines associations of a range of detailed sleep characteristics and breast and prostate cancer risk in a large-scale population-based case-control study, MCC-Spain. A total of 1738 incident breast cancer cases, 1112 prostate cancer cases and frequency matched controls (n = 1910, and 1493 respectively) were recruited. Detailed data on habitual sleep duration, quality, timing, and daytime napping (siesta) were collected at recruitment. Additional data on sleep habits during both the previous year and at age 40 years were also subsequently captured. Adjusted odds ratios (ORs) and 95% confidence intervals (CI) were estimated. There were no associations of habitual sleep duration (h), timing of sleep, or any or specific sleep problems, and either breast and prostate cancer risk. There was a significant positive association of ever taking habitual siestas at recruitment and breast cancer risk (OR = 1.22, 95% CI 1.06-1.42), which strengthened with increased frequency or duration. There were also significant positive associations observed for both breast and prostate cancer, among those reporting recent sleep problems, but not sleep problems at age 40 years, in a subsequent circadian questionnaire. Adverse associations with siesta and disturbed sleep during the previous year likely reflect symptoms of developing/diagnosed cancer and comorbidities. Overall, there was no clear association between various sleep characteristics and breast or prostate cancer risk observed. |
Note: | Reproducció del document publicat a: https://doi.org/10.1038/s41598-022-25789-9 |
It is part of: | Scientific Reports, 2022, vol. 12, num. 1, p. 21807 |
URI: | http://hdl.handle.net/2445/194052 |
Related resource: | https://doi.org/10.1038/s41598-022-25789-9 |
ISSN: | 2045-2322 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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File | Description | Size | Format | |
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s41598-022-25789-9.pdf | 1.03 MB | Adobe PDF | View/Open |
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