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http://hdl.handle.net/2445/194365
Title: | Pancreatic Organoids for Regenerative Medicine and Cancer Research |
Author: | Casamitjana, Joan Espinet, Elisa Rovira, Meritxell |
Keywords: | Pàncrees Diabetis Medicina regenerativa Medicina personalitzada Pancreas Diabetes Regenerative medicine Personalized medicine |
Issue Date: | 3-May-2022 |
Publisher: | Frontiers Media |
Abstract: | In recent years, the development of ex vivo organoid cultures has gained substantial attention as a model to study regenerative medicine and diseases in several tissues. Diabetes and pancreatic ductal adenocarcinoma (PDAC) are the two major devastating diseases affecting the pancreas. Suitable models for regenerative medicine in diabetes and to accurately study PDAC biology and treatment response are essential in the pancreatic field. Pancreatic organoids can be generated from healthy pancreas or pancreatic tumors and constitute an important translational bridge between in vitro and in vivo models. Here, we review the rapidly emerging field of pancreatic organoids and summarize the current applications of the technology to tissue regeneration, disease modelling, and drug screening. |
Note: | Reproducció del document publicat a: https://doi.org/10.3389/fcell.2022.886153 |
It is part of: | Frontiers In Cell And Developmental Biology, 2022, vol. 10 |
URI: | http://hdl.handle.net/2445/194365 |
Related resource: | https://doi.org/10.3389/fcell.2022.886153 |
ISSN: | 2296-634X |
Appears in Collections: | Articles publicats en revistes (Ciències Fisiològiques) |
Files in This Item:
File | Description | Size | Format | |
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724662.pdf | 1.63 MB | Adobe PDF | View/Open |
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