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DC Field | Value | Language |
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dc.contributor.author | Vilaseca González, Isabel | - |
dc.contributor.author | Avilés Jurado, Francesc Xavier | - |
dc.contributor.author | Valduvieco, Izaskun | - |
dc.contributor.author | Berenguer, Joan | - |
dc.contributor.author | Grau, Juan José | - |
dc.contributor.author | Baste, Neus | - |
dc.contributor.author | Muxí Pradas, África | - |
dc.contributor.author | Castillo, Paola | - |
dc.contributor.author | Lehrer, Eduardo | - |
dc.contributor.author | Jordana, Marta | - |
dc.contributor.author | Ramírez Ruiz, Rosa Delia | - |
dc.contributor.author | Costa, José Miguel | - |
dc.contributor.author | Oleaga Zufiría, Laura | - |
dc.contributor.author | Bernal Sprekelsen, Manuel | - |
dc.date.accessioned | 2023-03-14T13:39:16Z | - |
dc.date.available | 2023-03-14T13:39:16Z | - |
dc.date.issued | 2021-09-27 | - |
dc.identifier.issn | 1043-3074 | - |
dc.identifier.uri | http://hdl.handle.net/2445/195211 | - |
dc.description.abstract | To evaluate the importance of larynx compartments in the prognosis of T3-T4a laryngeal cancer treated with transoral laser microsurgery. Background: To evaluate the importance of larynx compartments in the prognosis of T3-T4a laryngeal cancer treated with transoral laser microsurgery. Methods: Two hundred and two consecutive pT3-T4a larynx carcinomas. Pre-epiglottic space involvement, anterior and posterior paraglottic space (PGS) involvement, vocal cord, and arytenoid mobility were determined. Local control with laser (LC), overall survival (OS), disease-specific survival (DSS), and laryngectomy-free survival (LFS) were evaluated. Results: The lowest LC was found in tumors with fixed arytenoid. In the multivariate analysis, positive margins (hazard ratio [HR] = 0.289 [0.085-0.979]) and anterior (HR = 0.278 [0.128-0.605]) and posterior (HR = 0.269 [0.115-0.630]) PGS invasion were independent factors of a reduced LC. Anterior (HR = 3.613 [1.537-8.495]) and posterior (HR = 5.195 [2.167-12.455]) PGS involvement were independent factors of total laryngectomy. Five-year OS, DSS, and LFS rates were 63.9%, 77.5%, and 77.5%, respectively. Patients with posterior PGS presented a reduced 5-year LFS. Conclusions: Tumor classification according to laryngeal compartmentalization depicts strong correlation with LC and LFS. | - |
dc.format.extent | 11 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | J. Wiley | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1002/hed.26878 | - |
dc.relation.ispartof | Head & Neck. Journal for the Sciences and Specialties of the Head and Neck, 2021, vol. 43, num. 12, p. 3832-3842 | - |
dc.relation.uri | https://doi.org/10.1002/hed.26878 | - |
dc.rights | cc-by-nc-nd (c) Vilaseca González, Isabel et al., 2021 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.source | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) | - |
dc.subject.classification | Càncer de laringe | - |
dc.subject.classification | Microcirurgia | - |
dc.subject.classification | Làsers en cirurgia | - |
dc.subject.classification | Cartílag | - |
dc.subject.classification | Teixit connectiu | - |
dc.subject.other | Larynx cancer | - |
dc.subject.other | Microsurgery | - |
dc.subject.other | Lasers in surgery | - |
dc.subject.other | Cartilage | - |
dc.subject.other | Connective tissue | - |
dc.title | Transoral laser microsurgery in locally advanced laryngeal cancer: Prognostic impact of anterior versus posterior compartments | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 721232 | - |
dc.date.updated | 2023-03-14T13:39:17Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 34569120 | - |
Appears in Collections: | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) |
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721232.pdf | 929.93 kB | Adobe PDF | View/Open |
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