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http://hdl.handle.net/2445/195560
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DC Field | Value | Language |
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dc.contributor.author | Díaz Feijoo, Berta | - |
dc.contributor.author | Agustí, Núria | - |
dc.contributor.author | Sebio, Raquel | - |
dc.contributor.author | López-Hernández, Antonio | - |
dc.contributor.author | Siso, Marina | - |
dc.contributor.author | Glickman, Ariel | - |
dc.contributor.author | Carreras Dieguez, Nuria | - |
dc.contributor.author | Fuste, Pere | - |
dc.contributor.author | Marina, Tiermes | - |
dc.contributor.author | Martínez-Egea, Judit | - |
dc.contributor.author | Aguilera, Laura | - |
dc.contributor.author | Perdomo, Juan | - |
dc.contributor.author | Pelaez, Amaia | - |
dc.contributor.author | López-Baamonde, Manuel | - |
dc.contributor.author | Navarro Ripoll, Ricard | - |
dc.contributor.author | Gimeno, Elena | - |
dc.contributor.author | Campero, Betina | - |
dc.contributor.author | Torné Bladé, Aureli | - |
dc.contributor.author | Martinez-Palli, Graciela | - |
dc.contributor.author | Arguis, María José | - |
dc.date.accessioned | 2023-03-17T18:49:32Z | - |
dc.date.available | 2023-03-17T18:49:32Z | - |
dc.date.issued | 2022-03-23 | - |
dc.identifier.issn | 2072-6694 | - |
dc.identifier.uri | http://hdl.handle.net/2445/195560 | - |
dc.description.abstract | Introduction: Treatment for advanced ovarian cancer (AOC) comprises cytoreductive surgery combined with chemotherapy. Multimodal prehabilitation programmes before surgery have demonstrated efficacy in postoperative outcomes in non-gynaecological surgeries. However, the viability and effects of these programmes on patients with AOC are unknown. We aimed to evaluate the feasibility and postoperative impact of a multimodal prehabilitation programme in AOC patients undergoing surgery. Methods: This single-centre, before-and-after intervention pilot study included 34 patients in two cohorts: the prehabilitation cohort prospectively included 15 patients receiving supervised exercise, nutritional optimisation, and psychological preparation from December 2019 to January 2021; the control cohort included 19 consecutive patients between January 2018 and November 2019. Enhanced Recovery After Surgery guidelines were followed. Results: The overall adherence to the multimodal prehabilitation programme was 80%, with 86.7% adherence to exercise training, 100% adherence to nutritional optimisation, and 80% adherence to psychological preparation. The median hospital stay was shorter in the prehabilitation cohort (5 (IQR, 4-6) vs. 7 days (IQR, 5-9) in the control cohort, p = 0.04). Differences in postoperative complications using the comprehensive complication index (CCI) were not significant (CCI score: 9.3 (SD 12.12) in the prehabilitation cohort vs. 16.61 (SD 16.89) in the control cohort, p = 0.08). The median time to starting chemotherapy was shorter in the prehabilitation cohort (25 (IQR, 23-25) vs. 35 days (IQR, 28-45) in the control cohort, p = 0.03). Conclusions: A multimodal prehabilitation programme before cytoreductive surgery is feasible in AOC patients with no major adverse effects, and results in significantly shorter hospital stays and time to starting chemotherapy. | - |
dc.format.extent | 12 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/cancers14071635 | - |
dc.relation.ispartof | Cancers, 2022, vol. 14, num. 7, p. 1635 | - |
dc.relation.uri | https://doi.org/10.3390/cancers14071635 | - |
dc.rights | cc-by (c) Díaz Feijoo, Berta et al., 2022 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) | - |
dc.subject.classification | Càncer d'ovari | - |
dc.subject.classification | Cirurgia ginecològica | - |
dc.subject.classification | Quimioteràpia del càncer | - |
dc.subject.classification | Malalts de càncer | - |
dc.subject.other | Ovarian cancer | - |
dc.subject.other | Gynecologic surgery | - |
dc.subject.other | Cancer chemotherapy | - |
dc.subject.other | Cancer patients | - |
dc.title | Feasibility of a Multimodal Prehabilitation Programme in Patients Undergoing Cytoreductive Surgery for Advanced Ovarian Cancer: A Pilot Study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 724414 | - |
dc.date.updated | 2023-03-17T18:49:32Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 35406407 | - |
Appears in Collections: | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) |
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724414.pdf | 2.08 MB | Adobe PDF | View/Open |
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