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http://hdl.handle.net/2445/197285
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DC Field | Value | Language |
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dc.contributor.author | Perra, Matteo | - |
dc.contributor.author | Manca, Maria Letizia | - |
dc.contributor.author | Tuberoso, Carlo I.G. | - |
dc.contributor.author | Caddeo, Carla | - |
dc.contributor.author | Marongiu, Francesca | - |
dc.contributor.author | Peris, Josè Esteban | - |
dc.contributor.author | Orrù, Germano | - |
dc.contributor.author | Ibba, Antonella | - |
dc.contributor.author | Fernàndez Busquets, Xavier | - |
dc.contributor.author | Fattouch, Sami | - |
dc.contributor.author | Bacchetta, Gianluigi | - |
dc.contributor.author | Manconi, Maria | - |
dc.date.accessioned | 2023-04-26T13:55:48Z | - |
dc.date.available | 2023-08-01T05:10:22Z | - |
dc.date.issued | 2022-08-01 | - |
dc.identifier.issn | 1878-5522 | - |
dc.identifier.uri | http://hdl.handle.net/2445/197285 | - |
dc.description.abstract | According to circular economy, wine-making by-products represent a fascinating biomass, which can be used for the sustainable exploitation of polyphenols and the development of new nanotechnological health-promoting products. In this study, polyphenols contained in the grape pomace were extracted by maceration with ethanol in an easy and low dissipative way. The obtained extract, rich in malvidin-3-glucoside, quercetin, procyanidin B2 and gallic acid, was incorporated into phospholipid vesicles tailored for intestinal delivery. To improve their performances, vesicles were enriched with gelatine or a maltodextrin (Nutriose®), or their combination (gelatine-liposomes, nutriosomes and gelatine-nutriosomes). The small (~147 nm) and negatively charged (~ −50 mV) vesicles were stable at different pH values mimicking saliva (6.75), gastric (1.20) and intestinal (7.00) environments. Vesicles effectively protected intestinal cells (Caco-2) from the oxidative stress and promoted the biofilm formation by probiotic bacteria. A preliminary evaluation of the vesicle feasibility at industrial levels was also performed, analysing the economic and energetic costs needed for their production. | ca |
dc.format.extent | 10 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | ca |
dc.publisher | Elsevier | ca |
dc.relation.isformatof | Postprint del document publicat a: https://doi.org/10.1016/j.ifset.2022.103103 | - |
dc.relation.ispartof | Innovative Food Science and Emerging Technologies, 2022, vol. 80 | - |
dc.relation.uri | https://doi.org/10.1016/j.ifset.2022.103103 | - |
dc.rights | cc by-nc-nd (c) Perra, Matteo et al, 2022 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC)) | - |
dc.subject.classification | Probiòtics | - |
dc.subject.classification | Raïms | - |
dc.subject.other | Probiotics | - |
dc.subject.other | Grapes | - |
dc.title | A green and cost-effective approach for the efficient conversion of grape byproducts into innovative delivery systems tailored to ensure intestinal protection and gut microbiota fortification | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Institut de Nanociència i Nanotecnologia (IN2UB)) Articles publicats en revistes (ISGlobal) Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC)) |
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File | Description | Size | Format | |
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2022_IFSET_AGreen_Perra_postprint.pdf | 472.27 kB | Adobe PDF | View/Open |
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