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http://hdl.handle.net/2445/197663
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DC Field | Value | Language |
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dc.contributor.author | Ortega Paz, Luis | - |
dc.contributor.author | Arévalos, Victor | - |
dc.contributor.author | Fernández Rodríguez, Diego | - |
dc.contributor.author | Jiménez Díaz, Víctor | - |
dc.contributor.author | Bañeras, Jordi | - |
dc.contributor.author | Campo, Gianluca | - |
dc.contributor.author | Rodríguez Santamarta, Miguel | - |
dc.contributor.author | Díaz, José Francisco | - |
dc.contributor.author | Scardino, Claudia | - |
dc.contributor.author | Gómez Álvarez, Zaira | - |
dc.contributor.author | Pernigotti, Alberto | - |
dc.contributor.author | Alfonso, Fernando | - |
dc.contributor.author | Amat Santos, Ignacio J. | - |
dc.contributor.author | Silvestro, Antonio | - |
dc.contributor.author | Rampa, Lorenzo | - |
dc.contributor.author | Torre Hernández, José M. de la | - |
dc.contributor.author | Bastidas, Gabriela | - |
dc.contributor.author | Gómez Lara, Josep | - |
dc.contributor.author | Bikdeli, Behnood | - |
dc.contributor.author | García García, Hector M. | - |
dc.contributor.author | Angiolillo, Dominick J. | - |
dc.contributor.author | Rodés Cabau, Josep | - |
dc.contributor.author | Sabaté, Manel | - |
dc.contributor.author | Brugaletta, Salvatore | - |
dc.contributor.author | The CV Covid-19 Registry Investigators | - |
dc.date.accessioned | 2023-05-08T11:11:35Z | - |
dc.date.available | 2023-05-08T11:11:35Z | - |
dc.date.issued | 2022-12-30 | - |
dc.identifier.uri | http://hdl.handle.net/2445/197663 | - |
dc.description.abstract | Background The long-term cardiovascular (CV) outcomes of COVID-19 have not been fully explored. Methods This was an international, multicenter, retrospective cohort study conducted between February and December 2020. Consecutive patients.18 years who underwent a real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for SARS-CoV2 were included. Patients were classified into two cohorts depending on the nasopharyngeal swab result and clinical status: confirmed COVID-19 (positive RT-PCR) and control (without suggestive symptoms and negative RT-PCR). Data were obtained from electronic records, and clinical follow-up was performed at 1-year. The primary outcome was CV death at 1-year. Secondary outcomes included arterial thrombotic events (ATE), venous thromboembolism (VTE), and serious cardiac arrhythmias. An independent clinical event committee adjudicated events. A Cox proportional hazards model adjusted for all baseline characteristics was used for comparing outcomes between groups. A prespecified landmark analysis was performed to assess events during the post-acute phase (31-365 days). Results A total of 4,427 patients were included: 3,578 (80.8%) in the COVID-19 and 849 (19.2%) control cohorts. At one year, there were no significant differences in the primary endpoint of CV death between the COVID-19 and control cohorts (1.4% vs. 0.8%; HRadj 1.28 [0.562.91]; p = 0.555), but there was a higher risk of all-cause death (17.8% vs. 4.0%; HRadj 2.82 [1.99-4.0]; p = 0.001). COVID-19 cohort had higher rates of ATE (2.5% vs. 0.8%, HRadj 2.26 [1.02-4.99]; p = 0.044), VTE (3.7% vs. 0.4%, HRadj 9.33 [2.93-29.70]; p = 0.001), and serious cardiac arrhythmias (2.5% vs. 0.6%, HRadj 3.37 [1.35-8.46]; p = 0.010). During the post-acute phase, there were no significant differences in CV death (0.6% vs. 0.7%; HRadj 0.67 [0.25-1.80]; p = 0.425), but there was a higher risk of deep vein thrombosis (0.6% vs. 0.0%; p = 0.028). Re-hospitalization rate was lower in the COVID-19 cohort compared to the control cohort (13.9% vs. 20.6%; p = 0.001). Conclusions At 1-year, patients with COVID-19 experienced an increased risk of all-cause death and adverse CV events, including ATE, VTE, and serious cardiac arrhythmias, but not CV death. | - |
dc.format.extent | 18 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Public Library of Science (PLoS) | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1371/journal.pone.0279333 | - |
dc.relation.ispartof | PLOS ONE, 2022, vol. 17, num. 12, p. e0279333 | - |
dc.relation.uri | https://doi.org/10.1371/journal.pone.0279333 | - |
dc.rights | cc by (c) Ortega Paz, Luis et al., 2022 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | Infeccions per coronavirus | - |
dc.subject.classification | Malalties cardiovasculars | - |
dc.subject.classification | COVID-19 | - |
dc.subject.classification | SARS-CoV-2 | - |
dc.subject.other | Coronavirus infections | - |
dc.subject.other | Cardiovascular diseases | - |
dc.subject.other | COVID-19 | - |
dc.subject.other | SARS-CoV-2 | - |
dc.title | One-year cardiovascular outcomes after coronavirus disease 2019: The cardiovascular COVID-19 registry | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2023-04-14T11:04:32Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.idimarina | 9334182 | - |
dc.identifier.pmid | 36583998 | - |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Medicina) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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journal.pone.0279333.pdf | 1.7 MB | Adobe PDF | View/Open |
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