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http://hdl.handle.net/2445/197785
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DC Field | Value | Language |
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dc.contributor.author | Garcia Exposito, Nerea | - |
dc.contributor.author | Ramos Izquierdo, Ricard | - |
dc.contributor.author | Navarro Perez, Valentin | - |
dc.contributor.author | Molina, Kevin | - |
dc.contributor.author | Arnaiz, Maria Dolores | - |
dc.contributor.author | Padrones, Susana | - |
dc.contributor.author | Ruffinelli, José Carlos | - |
dc.contributor.author | Santos, Cristina | - |
dc.contributor.author | Guedea Edo, Ferran | - |
dc.contributor.author | Navarro Martin, Arturo | - |
dc.date.accessioned | 2023-05-10T14:32:57Z | - |
dc.date.available | 2023-05-10T14:32:57Z | - |
dc.date.issued | 2023-02-13 | - |
dc.identifier.issn | 2072-6694 | - |
dc.identifier.uri | http://hdl.handle.net/2445/197785 | - |
dc.description.abstract | Background: Surgery and stereotactic body radiotherapy (SBRT) are two of the options available as local treatments for pulmonary oligometastases from colorectal cancer (CRC). We hypothesized that SBRT would have, at least, a similar local control rate to surgery. Methods: We identified an initial cohort of 100 patients with CRC who received SBRT or surgery for lung metastases. This was then narrowed down to 75 patients: those who underwent surgery (n = 50) or SBRT (n = 25) as their first local thoracic treatment between 1 January 2004 and 29 December 2017. The Kaplan-Meier method was used to calculate lung-progression-free survival (L-PFS) and overall survival (OS). Results: The 1 and 2-year L-PFS was 85% and 70% in the surgical group and 87% and 71% in the SBRT group, respectively (p = 0.809). No significant differences were found between the two groups in terms of OS. The biologically effective dose (BED), age and initial CRC stage did not have a significant effect on local control or survival. No grade 3 or above acute- or late-toxicity events were reported. Conclusions: These results add retrospective evidence that SBRT and surgery have similar results in terms of OS and local control in patients with lung oligometastases from CRC. | - |
dc.format.extent | 13 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/cancers15041195 | - |
dc.relation.ispartof | Cancers, 2023, vol. 15, num. 4, p. 1195 | - |
dc.relation.uri | https://doi.org/10.3390/cancers15041195 | - |
dc.rights | cc-by (c) Garcia Exposito, Nerea et al., 2023 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Càncer colorectal | - |
dc.subject.classification | Metàstasi | - |
dc.subject.classification | Mastectomia | - |
dc.subject.classification | Radioteràpia | - |
dc.subject.other | Colorectal cancer | - |
dc.subject.other | Metastasis | - |
dc.subject.other | Mastectomy | - |
dc.subject.other | Radiotherapy | - |
dc.title | Stereotactic body radiotherapy versus surgery for lung metastases from colorectal cancer: single-institution results | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 732600 | - |
dc.date.updated | 2023-05-10T14:32:57Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 36831537 | - |
dc.identifier.pmid | 36831537 | - |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Patologia i Terapèutica Experimental) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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732600.pdf | 2.44 MB | Adobe PDF | View/Open |
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