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Title: Species and biotypes of Streptococcus bovis causing infective endocarditis
Author: Corredoira, Juan
Grau, Inma
Garcia-Rodriguez, Jose Francisco
Romay, Eva
Cuervo Requena, Guillermo
Berbel, Dàmaris
Ayuso, Blanca
García País, Maria José
Rabuñal, Román
García Garrote, Fernando
Alonso, Maria Pilar
Pallarés Giner, Roman
Keywords: Endocarditis
Càncer colorectal
Colorectal cancer
Issue Date: 5-Jan-2023
Publisher: Elsevier
Abstract: Introduction: Streptococcus bovis/equinus complex (SBEC) is a major cause of infective endocarditis (IE), although its incidence varies greatly depending on the geographical area. The characteristics of IE caused by Streptococcus gallolyticus susp. gallolyticus are well known; there are hardly any descriptions of IE caused by other species or biotypes. Methods: Retrospective cohort study, from 1990 to 2019, of all SBEC IE in adults in three Spanish hospitals, Lugo (LH), Barcelona (BH) and Ferrol (FH) where the population is mainly rural, urban and mixed, respectively. The incidence of IE was analyzed in 3 areas. Clinical characteristics of IE (277 cases, 258 biotyped) were compared according to SBEC species and biotypes. Results: There are significant differences between the incidence of SBEC IE in HL (27.9/106) vs. HF and HB (8.8 and 7,1, respectively, p<0.001). We found significant differences (SbI vs. SbII) in mean age (68.5 vs. 73 years; p<0.01), duration of symptoms before diagnosis (46.9±46.5 vs. 30.4±40.9 days; p<0.01), presence of comorbidities: 39.1% (78) vs. 54.2% (32; p<0.04), predisposing heart illness:62.3% (124) vs. 81.3% (48; p<0.006), particularly, prosthetic or intravascular devices IE: 24.6% (49) vs. 52.4% (31; p<0.001), bi-valve involvement:23.6% (47) vs. 11.8% (7; p<0.05) and heart failure: 24.6% (49) vs. 38.9% (23; p<0.03). There were no significant differences in embolic events, need for surgery or mortality. The association with CRC was high in both groups: 77.7% vs. 66.6%. Conclusions: IE due to SBEC has geographical variations in incidence and different clinical characteristics among biotypes. The association with CRC was high.
Note: Versió postprint del document publicat a:
It is part of: Enfermedades Infecciosas y Microbiologia Clinica, 2023, vol. S2529, num. 22, p. 304-305
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ISSN: 0213-005X
Appears in Collections:Articles publicats en revistes (Ciències Clíniques)

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