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http://hdl.handle.net/2445/198403
Title: | Characteristics of long-COVID among older adults: a cross-sectional study |
Author: | Daitch, Vered Yelin, Dana Awwad, Muhammad Guaraldi, Giovanni Milić, Jovana Mussini, Cristina Falcone, Marco Tiseo, Giusy Carrozzi, Laura Pistelli, Francesco Nehme, Mayssam Guessous, Idris Kaiser, Laurent Vetter, Pauline Bordas Martínez, Jaume Durà Miralles, Xavier Peleato Catalan, Dolores Gudiol González, Carlota Shapira Lichter, Irit Abecasis, Donna Leibovici, Leonard Yahav, Dafna Margalit, Ili ESCMID study group for infections in the elderly (ESGIE) |
Keywords: | COVID-19 SARS-CoV-2 Persones grans COVID-19 SARS-CoV-2 Older people |
Issue Date: | Dec-2022 |
Publisher: | Elsevier B.V. |
Abstract: | Objectives: To describe long-COVID symptoms among older adults and to assess the risk factors for two common long-COVID symptoms: fatigue and dyspnea. Methods: This is a multicenter, prospective cohort study conducted in Israel, Switzerland, Spain, and Italy. Individuals were included at least 30 days after their COVID-19 diagnosis. We compared long-COVID symptoms between elderly (aged >65 years) and younger individuals (aged 18-65 years) and conducted univariate and multivariable analyses for the predictors of long-COVID fatigue and dyspnea. Results: A total of 2333 individuals were evaluated at an average of 5 months (146 days [95% confidence interval 142-150]) after COVID-19 onset. The mean age was 51 years, and 20.5% were aged >65 years. Older adults were more likely to be symptomatic, with the most common symptoms being fatigue (38%) and dyspnea (30%); they were more likely to complain of cough and arthralgia and have abnormal chest imaging and pulmonary function tests. Independent risk factors for long-COVID fatigue and dyspnea included female gender, obesity, and closer proximity to COVID-19 diagnosis; older age was not an independent predictor. Conclusion: Older individuals with long-COVID have different persisting symptoms, with more pronounced pulmonary impairment. Women and individuals with obesity are at risk. Further research is warranted to investigate the natural history of long-COVID among the elderly population and to assess possible interventions aimed at promoting rehabilitation and well-being. |
Note: | Reproducció del document publicat a: https://doi.org/10.1016/j.ijid.2022.09.035 |
It is part of: | International Journal of Infectious Diseases, 2022, vol. 125, p. 287-293 |
URI: | http://hdl.handle.net/2445/198403 |
Related resource: | https://doi.org/10.1016/j.ijid.2022.09.035 |
ISSN: | 1201-9712 |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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