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http://hdl.handle.net/2445/198562
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DC Field | Value | Language |
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dc.contributor.author | Melero Ollonarte, Juan Luis | - |
dc.contributor.author | Lidón Moyano, Cristina | - |
dc.contributor.author | Perez Ortuño, Raúl | - |
dc.contributor.author | Fu Balboa, Marcela | - |
dc.contributor.author | Ballbè i Gibernau, Montse | - |
dc.contributor.author | Martín Sánchez, Juan Carlos | - |
dc.contributor.author | González Barrón, Adrián | - |
dc.contributor.author | Cartanyà Hueso, Àurea | - |
dc.contributor.author | Pascual, José A. | - |
dc.contributor.author | Fernández Muñoz, Esteve | - |
dc.contributor.author | Martínez Sánchez, Jose M. | - |
dc.date.accessioned | 2023-05-29T10:43:25Z | - |
dc.date.issued | 2023-01-19 | - |
dc.identifier.issn | 1873-6327 | - |
dc.identifier.uri | http://hdl.handle.net/2445/198562 | - |
dc.description.abstract | Introduction: This study aims to address the existing gap in the literature, while adding evidence, by comparing tobacco-specific biomarkers (cotinine and nitrosamines: NNK, NNAL, NNN), and other biomarkers of e-cigarette use (humectants: glycerol, 1,2-PD, 1,3-PD) according to five study groups. Methods: A pooling analysis including two different studies was conducted. In both analyses, we took saliva samples from smokers (n = 409) and non-smokers (n = 154), dual tobacco and e-cig users (n = 92), exclusive e-cig user with nicotine (n = 158), and exclusive e-cig users without nicotine (n = 38). We analyzed and compared the geometric means (GM) and geometric standard deviations (GSD) of the concentration of tobacco-specific biomarkers, and e-cigarette biomarkers among groups. We used log-linear models adjusted for sex and age to model the change percentage and their 95% confidence intervals. Results: Cotinine was significantly higher in nicotine consumers and in e-cigarette users without nicotine when compared to non-smokers. TSNAs were generally significantly lower in non-smokers and higher in nicotine consumers. NNN and NNAL were lower in e-cigarette users with nicotine comparted to smokers, and NNN was higher in e-cigarette users without nicotine when compared to non-smokers. No differences were found in humectant biomarkers between e-cigarette groups. Conclusions: Although there was a reduction in TSNAs in e-cigarette exclusive users compared to smokers, and a reduction of cotinine concentrations in e-cigarette exclusive users without nicotine compared to smokers, there are still high levels of these biomarkers when compared to non-smokers, which may be a clue towards the harmful effect of e-cigarettes. | ca |
dc.format.extent | 26 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | ca |
dc.publisher | Elsevier BV | ca |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1016/j.addbeh.2023.107616 | - |
dc.relation.ispartof | Addictive Behaviors, 2023, vol. 140, p. 107616 | - |
dc.relation.uri | https://doi.org/10.1016/j.addbeh.2023.107616 | - |
dc.rights | cc by-nc-nd (c) Elsevier, 2023 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Cigarretes electròniques | - |
dc.subject.classification | Marcadors bioquímics | - |
dc.subject.classification | Tabac | - |
dc.subject.classification | Fumadors | - |
dc.subject.other | Electronic cigarettes | - |
dc.subject.other | Biochemical markers | - |
dc.subject.other | Tobacco | - |
dc.subject.other | Cigarette smokers | - |
dc.title | Specific biomarker comparison in current smokers, e-cigarette users, and non-smokers | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.date.updated | 2023-05-05T11:35:10Z | - |
dc.rights.accessRights | info:eu-repo/semantics/embargoedAccess | ca |
dc.embargo.lift | 2025-01-19 | - |
dc.date.embargoEndDate | info:eu-repo/date/embargoEnd/2025-01-19 | ca |
dc.identifier.pmid | 36680837 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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Melero-Ollonarte.pdf | 1.39 MB | Adobe PDF | View/Open Request a copy |
Document embargat fins el 19-1-2025
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