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http://hdl.handle.net/2445/198665
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DC Field | Value | Language |
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dc.contributor.author | Hernández Rubio, Anna | - |
dc.contributor.author | Sanvisens Bergé, Arantza | - |
dc.contributor.author | Barbier Torres, Lucía | - |
dc.contributor.author | Blanes, Rafael | - |
dc.contributor.author | Miquel de Montagut, Laia | - |
dc.contributor.author | Torrens, Marta | - |
dc.contributor.author | Rubio, Gabriel | - |
dc.contributor.author | Bolao, Ferran | - |
dc.contributor.author | Zuluaga, Paola | - |
dc.contributor.author | Fuster, Daniel | - |
dc.contributor.author | Rodríguez de Fonseca, Fernando | - |
dc.contributor.author | Farré Albaladejo, Magí | - |
dc.contributor.author | Muga, Robert | - |
dc.contributor.author | CohRTA Study | - |
dc.contributor.author | Papasseit, Esther | - |
dc.contributor.author | Pérez Mañá, Clara | - |
dc.contributor.author | Poyatos, Lourdes | - |
dc.contributor.author | García Marchena, Nuria | - |
dc.contributor.author | Abellí, Enric | - |
dc.contributor.author | Short, Antoni | - |
dc.contributor.author | Moranta, Catalina | - |
dc.contributor.author | Sion, Ana | - |
dc.contributor.author | Ortega, Lluisa | - |
dc.contributor.author | Bruguera, Pol | - |
dc.contributor.author | Caballeria, Elsa | - |
dc.contributor.author | Messeguer, Ana | - |
dc.contributor.author | Fonseca, Francina | - |
dc.contributor.author | Mestre Pinto, Juan Ignacio | - |
dc.contributor.author | Alías, María | - |
dc.contributor.author | Dinamarca, Fernando | - |
dc.contributor.author | Pavón Morón, Francisco Javier | - |
dc.contributor.author | Araos, Pedro | - |
dc.contributor.author | Flores López, María | - |
dc.contributor.author | Serrano, Antonia | - |
dc.contributor.author | Marcos, Miguel | - |
dc.contributor.author | Martín González, M. Candelaria | - |
dc.contributor.author | Pérez Hernández, Onán | - |
dc.contributor.author | Manzanares, Jorge | - |
dc.contributor.author | Illescas, Lucía | - |
dc.date.accessioned | 2023-05-30T08:12:12Z | - |
dc.date.available | 2023-05-30T08:12:12Z | - |
dc.date.issued | 2023-04-01 | - |
dc.identifier.issn | 1879-0046 | - |
dc.identifier.uri | http://hdl.handle.net/2445/198665 | - |
dc.description.abstract | Introduction: Hypomagnesemia (hypoMg) has not yet been extensively studied in alcohol use disorder (AUD) . We hypothesize that chronic, excessive alcohol consumption favors oxidative stress and pro-inflammatory alterations that may be exacerbated by hypoMg. The objective of this study was to analyze the prevalence and associations of hypoMg in AUD.Patients and Methods: Cross-sectional study in patients admitted for a first treatment of AUD in six tertiary centers between 2013 and 2020. Socio-demographic, alcohol use characteristics, and blood parameters were ascertained at admission.Results: 753 patients (71% men) were eligible; age at admission was 48 years [IQR, 41-56 years]. Prevalence of hypoMg was 11.2%, higher than that observed for hypocalcemia (9.3%), hyponatremia (5.6%), and hypokalemia (2.8%). HypoMg was associated with older age, longer duration of AUD, anemia, higher erythrocyte sedimen-tation rate, gamma-glutamyl transpeptidase, glucose levels, advanced liver fibrosis (FIB-4 >= 3.25) and estimated glomerular filtration rate (eGFR) < 60 mL/min. In multivariate analysis, advanced liver fibrosis (OR, 8.91; 95% CI, 3.3-23.9) and eGFR < 60 mL (OR, 5.2; 95% CI, 1.0-26.2) were the only factors associated with hypoMg.Conclusions: Mg deficiency in AUD is associated with liver damage and glomerular dysfunction suggesting that both comorbidities should be assessed in the course of serum hypoMg. | - |
dc.format.extent | 7 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1016/j.drugalcdep.2023.109822 | - |
dc.relation.ispartof | Drug and Alcohol Dependence, 2023, vol. 245 | - |
dc.relation.uri | https://doi.org/10.1016/j.drugalcdep.2023.109822 | - |
dc.rights | cc by-nc-nd (c) Hernández Rubio, Anna et al, 2023 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Alcoholisme | - |
dc.subject.classification | Dèficit de magnesi | - |
dc.subject.other | Alcoholism | - |
dc.subject.other | Magnesium deficiency diseases | - |
dc.title | Associations of hypomagnesemia in patients seeking a first treatment of alcohol use disorder | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2023-05-29T12:05:01Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 36893509 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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1-s2.0-S0376871623000601-main.pdf | 638.08 kB | Adobe PDF | View/Open |
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