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http://hdl.handle.net/2445/198674
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DC Field | Value | Language |
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dc.contributor.author | De Luca, Giuseppe | - |
dc.contributor.author | Algowhary, Magdy | - |
dc.contributor.author | Uguz, Berat | - |
dc.contributor.author | Oliveira, Dinaldo C. | - |
dc.contributor.author | Ganyukov, Vladimir | - |
dc.contributor.author | Busljetik, Oliver | - |
dc.contributor.author | Cercek, Miha | - |
dc.contributor.author | Okkels Jensen, Lisette | - |
dc.contributor.author | Loh, Poay Huan | - |
dc.contributor.author | Calmac, Lucian | - |
dc.contributor.author | Roura i Ferrer, Gerard | - |
dc.contributor.author | Quadros, Alexandre | - |
dc.contributor.author | Milewski, Marek | - |
dc.contributor.author | Scotto D’uccio, Fortunato | - |
dc.contributor.author | Von Birgelen, Clemens | - |
dc.contributor.author | Versaci, Francesco | - |
dc.contributor.author | Ten Berg, Jurrien | - |
dc.contributor.author | Casella, Gianni | - |
dc.contributor.author | Wong Sung Lung, Aaron | - |
dc.contributor.author | Kala, Petr | - |
dc.contributor.author | Díez Gil, José Luis | - |
dc.contributor.author | Carrillo, Xavier | - |
dc.contributor.author | Dirksen, Maurits | - |
dc.contributor.author | Becerra Munoz, Victor | - |
dc.contributor.author | Kang-yin Lee, Michael | - |
dc.contributor.author | Arifa Juzar, Dafsah | - |
dc.contributor.author | De Moura Joaquim, Rodrigo | - |
dc.contributor.author | Paladino, Roberto | - |
dc.contributor.author | Milicic, Davor | - |
dc.contributor.author | Davlouros, Periklis | - |
dc.contributor.author | Bakraceski, Nikola | - |
dc.contributor.author | Zilio, Filippo | - |
dc.contributor.author | Donazzan, Luca | - |
dc.contributor.author | Kraaijeveld, Adriaan | - |
dc.contributor.author | Galasso, Gennaro | - |
dc.contributor.author | Arpad, Lux | - |
dc.contributor.author | Marinucci, Lucia | - |
dc.contributor.author | Guiducci, Vincenzo | - |
dc.contributor.author | Menichelli, Maurizio | - |
dc.contributor.author | Scoccia, Alessandra | - |
dc.contributor.author | Hatice Yamac, Aylin | - |
dc.contributor.author | Ugur Mert, Kadir | - |
dc.contributor.author | Flores Rios, Xacobe | - |
dc.contributor.author | Kovarnik, Tomas | - |
dc.contributor.author | Kidawa, Michal | - |
dc.contributor.author | Moreu, Josè | - |
dc.contributor.author | Flavien, Vincent | - |
dc.contributor.author | Fabris, Enrico | - |
dc.contributor.author | Lozano Martínez-Luengas, Iñigo | - |
dc.contributor.author | Boccalatte, Marco | - |
dc.contributor.author | Bosa Ojeda, Francisco | - |
dc.contributor.author | Arellano Serrano, Carlos | - |
dc.contributor.author | Caiazzo, Gianluca | - |
dc.contributor.author | Cirrincione, Giuseppe | - |
dc.contributor.author | Kao, Hsien Li | - |
dc.contributor.author | Sanchis Forés, Juan | - |
dc.contributor.author | Vignali, Luigi | - |
dc.contributor.author | Pereira, Helder | - |
dc.contributor.author | Manzo Silberman, Stephane | - |
dc.contributor.author | Ordoñez, Santiago | - |
dc.contributor.author | Arat Özkan, Alev | - |
dc.contributor.author | Scheller, Bruno | - |
dc.contributor.author | Lehitola, Heidi | - |
dc.contributor.author | Teles, Rui | - |
dc.contributor.author | Mantis, Christos | - |
dc.contributor.author | Antti, Ylitalo | - |
dc.contributor.author | Brum Silveira, João António | - |
dc.contributor.author | Zoni, Cesar Rodrigo | - |
dc.contributor.author | Bessonov, Ivan | - |
dc.contributor.author | Uccello, Giuseppe | - |
dc.contributor.author | Kochiadakis, George | - |
dc.contributor.author | Alexopulos, Dimitrios | - |
dc.contributor.author | Uribe, Carlos E. | - |
dc.contributor.author | Kanakakis, John | - |
dc.contributor.author | Faurie, Benjamin | - |
dc.contributor.author | Gabrielli, Gabriele | - |
dc.contributor.author | Gutierrez Barrios, Alejandro | - |
dc.contributor.author | Bachini, Juan Pablo | - |
dc.contributor.author | Rocha, Alex | - |
dc.contributor.author | Tam, Frankie C. C. | - |
dc.contributor.author | Rodriguez, Alfredo | - |
dc.contributor.author | Lukito, Antonia Anna | - |
dc.contributor.author | Saint Joy, Veauthyelau | - |
dc.contributor.author | Pessah, Gustavo | - |
dc.contributor.author | Tuccillo, Andrea | - |
dc.contributor.author | Ielasi, Alfonso | - |
dc.contributor.author | Cortese, Giuliana | - |
dc.contributor.author | Parodi, Guido | - |
dc.contributor.author | Abed Burgadha, Mohammed | - |
dc.contributor.author | Kedhi, Elvin | - |
dc.contributor.author | Lamelas, Pablo | - |
dc.contributor.author | Suryapranata, Harry | - |
dc.contributor.author | Nardin, Matteo | - |
dc.contributor.author | Verdoia, Monica | - |
dc.date.accessioned | 2023-05-30T12:20:26Z | - |
dc.date.available | 2023-05-30T12:20:26Z | - |
dc.date.issued | 2023-03-08 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | http://hdl.handle.net/2445/198674 | - |
dc.description.abstract | Background: The constraints in the management of patients with ST-segment elevation myocardial infarction (STEMI) during the COVID-19 pandemic have been suggested to have severely impacted mortality levels. The aim of the current analysis is to evaluate the age-related effects of the COVID-19 pandemic on mechanical reperfusion and 30-day mortality for STEMI within the registry ISACS-STEMI COVID-19. Methods: This retrospective multicenter registry was performed in high-volume PPCI centers on four continents and included STEMI patients undergoing PPCI in March-June 2019 and 2020. Patients were divided according to age (< or >= 75 years). The main outcomes were the incidence and timing of PPCI, (ischemia time longer than 12 h and door-to-balloon longer than 30 min), and in-hospital or 30-day mortality. Results: We included 16,683 patients undergoing PPCI in 109 centers. In 2020, during the pandemic, there was a significant reduction in PPCI as compared to 2019 (IRR 0.843 (95%-CI: 0.825-0.861, p < 0.0001). We found a significant age-related reduction (7%, p = 0.015), with a larger effect on elderly than on younger patients. Furthermore, we observed significantly higher 30-day mortality during the pandemic period, especially among the elderly (13.6% vs. 17.9%, adjusted HR (95% CI) = 1.55 [1.24-1.93], p < 0.001) as compared to younger patients (4.8% vs. 5.7%; adjusted HR (95% CI) = 1.25 [1.05-1.49], p = 0.013), as a potential consequence of the significantly longer ischemia time observed during the pandemic. Conclusions: The COVID-19 pandemic had a significant impact on the treatment of patients with STEMI, with a 16% reduction in PPCI procedures, with a larger reduction and a longer delay to treatment among elderly patients, which may have contributed to increase in-hospital and 30-day mortality during the pandemic. | - |
dc.format.extent | 14 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI AG | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/jcm12062116 | - |
dc.relation.ispartof | Journal of Clinical Medicine, 2023, vol. 12, num. 6, p. 2116 | - |
dc.relation.uri | https://doi.org/10.3390/jcm12062116 | - |
dc.rights | cc by (c) De Luca, Giuseppe et al., 2023 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Pandèmia de COVID-19, 2020- | - |
dc.subject.classification | Infart de miocardi | - |
dc.subject.classification | Mortalitat | - |
dc.subject.classification | Factors d'edat en les malalties | - |
dc.subject.other | COVID-19 Pandemic, 2020- | - |
dc.subject.other | Myocardial infarction | - |
dc.subject.other | Mortality | - |
dc.subject.other | Age factors in disease | - |
dc.title | Age-Related Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2023-05-29T10:37:22Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 36983119 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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jcm-12-02116.pdf | 1.34 MB | Adobe PDF | View/Open |
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