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http://hdl.handle.net/2445/200226
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DC Field | Value | Language |
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dc.contributor.author | Baxarias, Marta | - |
dc.contributor.author | Jornet-Rius, Oriol | - |
dc.contributor.author | Donato, Giulia | - |
dc.contributor.author | Mateu, Cristina | - |
dc.contributor.author | Alcover Amengual, Maria Magdalena | - |
dc.contributor.author | Pennisi, Maria Grazia | - |
dc.contributor.author | Solano-Gallego, Laia | - |
dc.date.accessioned | 2023-07-03T11:17:12Z | - |
dc.date.available | 2023-07-03T11:17:12Z | - |
dc.date.issued | 2023-05-16 | - |
dc.identifier.issn | 2076-2615 | - |
dc.identifier.uri | http://hdl.handle.net/2445/200226 | - |
dc.description.abstract | Canine leishmaniosis caused by Leishmania infantum is a disease with a wide range of clinical manifestations. Epidemiological serosurveys performed in Europe often lack a thorough assessment of clinical health status of studied dogs. The aim of this study was to evaluate signalment, immunological and parasitological status and clinicopathological findings of L. infantum-seropositive apparently healthy dogs (n = 212) living in endemic areas. Routine laboratory tests, endpoint inhouse ELISA to quantify the anti-Leishmania antibodies, blood Leishmania qPCR and IFN-ELISA were performed. All dogs enrolled were L. infantum-seropositive and were classified as healthy (n = 105) or sick (n = 107) according to LeishVet guidelines. The sick group presented a higher proportion of medium to high antibody levels and positive qPCR and lower IFN-concentration compared to the healthy group. Sick dogs were mostly classified in LeishVet stage IIa. Biochemical alterations (98%) were the most common clinicopathological findings, with fewer urinary tract (46%) and hematological (40%) alterations. Apparently healthy L. infantum-seropositive dogs can be classified between truly healthy dogs and sick dogs with clinicopathological findings. Sick dogs presented medium to high seropositivity and parasitemia and low IFN- concentrations, and their most common clinicopathological abnormalities were serum protein alterations followed by proteinuria and lymphopenia. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/ani13101649 | - |
dc.relation.ispartof | Animals, 2023 | - |
dc.relation.uri | https://doi.org/10.3390/ani13101649 | - |
dc.rights | cc-by (c) Baxarias, Marta et al., 2023 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Biologia, Sanitat i Medi Ambient) | - |
dc.subject.classification | Leishmània | - |
dc.subject.classification | Gossos | - |
dc.subject.classification | Malalties infeccioses en els animals | - |
dc.subject.other | Leishmania | - |
dc.subject.other | Dogs | - |
dc.subject.other | Communicable diseases in animals | - |
dc.title | Signalment, Immunological and Parasitological Status and Clinicopathological Findings of Leishmania-Seropositive Apparently Healthy Dogs | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 733701 | - |
dc.date.updated | 2023-07-03T11:17:12Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Biologia, Sanitat i Medi Ambient) |
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File | Description | Size | Format | |
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733701.pdf | 380.94 kB | Adobe PDF | View/Open |
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