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http://hdl.handle.net/2445/200868
Title: | Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia |
Author: | Larriba, Sara Sánchez Herrero, Jose Francisco Pluvinet Ortega, Raquel López Rodrigo, Olga Bassas, Lluís Sumoy, Lauro |
Keywords: | Esterilitat masculina Investigació mèdica Male sterility Medicine research |
Issue Date: | 27-May-2023 |
Publisher: | Wiley |
Abstract: | Background: Non-invasive molecular biomarkers for classifying azoospermia by origin into either obstructive or non-obstructive/secretory azoospermia, as well as for inferring the spermatogenic reserve of the testis of non-obstructive/secretory azoospermia patients, are of great interest for testicular sperm retrieval outcome prediction for assisted reproduction. Prior analyses of semen small non-coding RNA expression in azoospermia have focused on microRNAs, but there has been a lack of attention on other regulatory small RNA species. In this regard, studying more in-depth expression changes of small non-coding RNA subtypes in small extracellular vesicles from semen of azoospermic individuals could be useful to select additional non-invasive biomarkers with diagnostic/prognostic purposes. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1111/andr.13461 |
It is part of: | Andrology, 2023 |
URI: | http://hdl.handle.net/2445/200868 |
Related resource: | https://doi.org/10.1111/andr.13461 |
ISSN: | 2047-2927 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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Larriba et al. 2023_Andrology.pdf | 3.67 MB | Adobe PDF | View/Open |
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