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http://hdl.handle.net/2445/201468
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DC Field | Value | Language |
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dc.contributor.author | Perelló Bratescu, Aina | - |
dc.contributor.author | Dürsteler, Christian | - |
dc.contributor.author | Álvarez- Carrera, Maria Asunción | - |
dc.contributor.author | Granés, Laura | - |
dc.contributor.author | Kostov, Belchin | - |
dc.contributor.author | Sisó Almirall, Antoni | - |
dc.date.accessioned | 2023-08-02T11:23:42Z | - |
dc.date.available | 2023-08-02T11:23:42Z | - |
dc.date.issued | 2022-01-31 | - |
dc.identifier.issn | 1660-4601 | - |
dc.identifier.uri | http://hdl.handle.net/2445/201468 | - |
dc.description.abstract | The prescription of strong opioids (SO) for chronic non-cancer pain (CNCP) is steadily increasing. This entails a high risk of adverse effects, a risk that increases with the concomitant prescription of SO with central nervous system depressant drugs and with the use of SO for non-recommended indications. In order to examine this concomitant risk prescription, we designed a descriptive, longitudinal, retrospective population-based study. Patients aged >= 15 years with a continued SO prescription for >= 3 months during 2013-2017 for CNCP were included. Of these, patients who had received concomitant prescriptions of SO and risk drugs (gabapentinoids, benzodiazepines and antidepressants) and those who had received immediate-release fentanyl (IRF) were selected. The study included 22,691 patients; 20,354 (89.7%) patients received concomitant risk prescriptions. Men and subjects with a higher socioeconomic status received fewer concomitant risk prescriptions. Benzodiazepines or Z-drugs were prescribed concomitantly with SO in 15,883 (70%) patients, antidepressants in 14,932 (65%) and gabapentinoids in 11,267 (49%), while 483 (21.32%) patients received IRF (2266 prescriptions in total) without a baseline SO. In conclusion, our study shows that a high percentage of patients prescribed SO for CNCP received concomitant prescriptions with known risks, as well as IRF for unauthorized indications. | - |
dc.format.extent | 10 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/ijerph19031652 | - |
dc.relation.ispartof | International Journal Of Environmental Research And Public Health, 2022, vol. 19, num. 3, p. 1652 | - |
dc.relation.uri | https://doi.org/10.3390/ijerph19031652 | - |
dc.rights | cc by (c) Perelló Bratescu, Aina et al., 2022 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) | - |
dc.subject.classification | Tractament del dolor | - |
dc.subject.classification | Avaluació del risc per la salut | - |
dc.subject.classification | Opiacis | - |
dc.subject.other | Pain treatment | - |
dc.subject.other | Health risk assessment | - |
dc.subject.other | Opioids | - |
dc.title | Risk Prescriptions of Strong Opioids in the Treatment of Chronic Non-Cancer Pain by Primary Care Physicians in Catalonia: Opicat Padris Project | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2023-07-04T07:29:57Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.idimarina | 9298488 | - |
dc.identifier.pmid | 35162674 | - |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) |
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File | Description | Size | Format | |
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Risk Prescriptions of Strong Opioids in the Treatment of Chronic Non-Cancer Pain by Primary Care Physicians_EnvironmentalResearch.pdf | 889.4 kB | Adobe PDF | View/Open |
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