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Title: | Hypoalbuminemia and advanced age are risk factors for delayed gastric emptying after pancreaticoduodenectomy |
Author: | Martín Santos, Silvia Sorribas Grifell, María Busquets Barenys, Juli Secanella Medayo, Lluis Peláez Serra, Nuria Carnaval, Thiago Videla Ces, Sebastián Fabregat Prous, Juan |
Keywords: | Cirurgia Factors de risc en les malalties Factors d'edat en les malalties Surgery Risk factors in diseases Age factors in disease |
Issue Date: | 12-Jun-2023 |
Publisher: | ARAN Ediciones |
Abstract: | Background:delayed gastric emptying (DGE) is one of the most common complications after pancreatoduodenectomy. It could be related to some baseline patient-related characteristics. This study aims to assess the predictive factors associated to DGE in the cohort of patients included in the PAUDA clinical trial. Methods:this study was a retrospective analysis based on the 80 patients included in a randomized clinical trial conducted and published by our group. A descriptive analysis and a bivariate regression model were carried out. Some factors were further scrutinized for associations using the Pearson correlation coefficient and, finally, a multiple regression model using a stepwise selection of variables was conducted. Results:DGE was diagnosed in 36 (45 %) out of 80 patients (DGE group). The number of patients older than 60 years old in the DGE group was greater than in the group without DGE (32 vs 28 patients, p = 0.009]). Likewise, the number of patients with a preoperative albumin < 35 g/L (18 vs 11 patients, p = 0.036); preoperative bilirubin > 200 & mu;mol/L (14 vs 8 patients, p = 0.039); postoperative haemorrhage (7 vs 1 patients, p = 0.011); postoperative intraabdominal abscess (12 vs 5 patients, p = 0.017); and postoperative biliary fistula (5 vs 0 patients, p = 0.011), was also greater in the DGE group. Two risk factors were associated with DGE: the patient's age at the time of surgery and preoperative hypoalbuminemia (serum albumin concentration & LE; 35g/L). Conclusions:the patient's age at the time of surgery and the preoperative nutritional status are independent risk factors to the development of DGE after pancreatoduodenectomy. |
Note: | Reproducció del document publicat a: https://doi.org/10.20960/nh.04287 |
It is part of: | Nutrición Hospitalaria, 2023, vol. 40, num. 3, p. 517-520 |
URI: | http://hdl.handle.net/2445/202644 |
Related resource: | https://doi.org/10.20960/nh.04287 |
ISSN: | 1699-5198 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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