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http://hdl.handle.net/2445/202901
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DC Field | Value | Language |
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dc.contributor.author | Fernández Luis, Sheila | - |
dc.contributor.author | Nhampossa, Tacilta | - |
dc.contributor.author | Fuente Soro, Laura | - |
dc.contributor.author | Augusto, Orvalho | - |
dc.contributor.author | Casellas, Aina | - |
dc.contributor.author | Bernardo, Edson | - |
dc.contributor.author | Ruperez, María | - |
dc.contributor.author | González, Raquel | - |
dc.contributor.author | Maculuve, Sónia Amós | - |
dc.contributor.author | Saura Lázaro, Anna | - |
dc.contributor.author | Menéndez, Clara | - |
dc.contributor.author | Naniche, Denise | - |
dc.contributor.author | López Varela, Elisa | - |
dc.date.accessioned | 2023-10-16T08:31:59Z | - |
dc.date.available | 2023-10-16T08:31:59Z | - |
dc.date.issued | 2020-05 | - |
dc.identifier.issn | 0891-3668 | - |
dc.identifier.uri | http://hdl.handle.net/2445/202901 | - |
dc.description.abstract | © 2020 Wolters Kluwer Health, Inc. All rights reserved. Background: There are 170,000 children living with HIV in 2017 in Mozambique. Scaling-up HIV care requires effective retention along the cascade. We sought to evaluate the pediatric cascade in HIV care at the Manhiça District Hospital. Methods: A prospective cohort of children <15 years was followed from enrollment in HIV care (January 2013 to December 2015) until December 2016. Loss to follow-up (LTFU) was defined as not attending the HIV hospital visits for ≥90 days following last visit attended. Results: From the 438 children included {median age at enrollment in care of 3,6 [interquartile range (IQR): 1.1-8.6] years}, 335 (76%) were antiretroviral therapy (ART) eligible and among those, 263 (78%) started ART at enrollment in HIV care. A total of 362 children initiated ART during the study period and the incidence rate of LTFU at 12, 24, and 36 months post-ART initiation was 41 [95% confidence interval (CI): 34-50], 34 (95% CI: 29-41), and 31 (95% CI: 27-37) per 100 children-years, respectively. Median time to LTFU was 5.8 (IQR: 1.4-12.7) months. Children 5-9 years of age had a lower risk of LTFU compared with children <1 year [adjusted subhazard ratio 0.36 (95% CI: 0.20-0.61)]. Re-engagement in care (RIC) was observed in 25% of the LTFU children. Conclusions: The high LTFU found in this study highlights the special attention that should be given to younger children during the first 6 months post-ART initiation to prevent LTFU. Once LTFU, only a quarter of those children return to the health unit. Elucidating factors associated with RIC could help to fine tune interventions which promote RIC. | - |
dc.format.extent | 28 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Wolters Kluwer Health | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1097/INF.0000000000002612 | - |
dc.relation.ispartof | Pediatric Infectious Disease Journal, 2020, vol. 39, num. 5, p. 429-434 | - |
dc.relation.uri | https://doi.org/10.1097/INF.0000000000002612 | - |
dc.rights | (c) Wolters Kluwer Health, 2020 | - |
dc.source | Articles publicats en revistes (ISGlobal) | - |
dc.subject.classification | Infeccions per VIH | - |
dc.subject.classification | Infants | - |
dc.subject.classification | Moçambic | - |
dc.subject.other | HIV infections | - |
dc.subject.other | Children | - |
dc.subject.other | Mozambique | - |
dc.title | Pediatric HIV care cascade in southern mozambique: Missed opportunities for early ART and re-engagement in care | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.date.updated | 2023-10-10T09:35:43Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.idimarina | 9197030 | - |
dc.identifier.pmid | 33636218 | - |
dc.identifier.pmid | 32091497 | - |
Appears in Collections: | Articles publicats en revistes (ISGlobal) |
Files in This Item:
File | Description | Size | Format | |
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32. PECA.pdf | 2.32 MB | Adobe PDF | View/Open |
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