Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/204983
Title: | Benchmarking DFT functionals for photophysics of pyranoflavylium cations |
Author: | Souza, Jhonathan R. Curutchet Barat, Carles E. Aoto, Yuri A. Homem-de-Mello, Paula |
Keywords: | Fototeràpia Química Phototherapy Chemistry |
Issue Date: | 28-Mar-2023 |
Publisher: | Elsevier B.V. |
Abstract: | An intense absorption, phosphorescence, a long triplet excited state lifetime and singlet oxygen generation capabilities are characteristics of pyranoflavylium cations, analogues to pyranoanthocyanidins originated in the maturation process of red wine. Such properties make these compounds potential photosensitizers to be applied in photodynamic therapy. In this context, the photophysical processes underlying that treatment critically depend on the electronic structure of the pyranoflavylium molecules. When employing density functional theory to describe the electronic structure of molecules, the choice of the most suitable functional is not trivial, and benchmark studies are needed to orient practitioners in the field. In this work, a benchmark of seven of the most commonly used density functionals in addressing the photophysical properties of a set of eight pyranoflavylium cations is reported. Ground and excited state geometries, molecular orbitals, and absorption, fluorescence and phosphorescence transition energies were calculated using density functional theory approaches, and evaluated and compared to experimental data and monoreferential wave function-based methodologies. Statistical analysis of the results indicates that global-hybrid functionals allow an excellent description of absorption and emission energies, with errors around 0.05 eV, while range-separated variants led to somewhat larger errors in the range 0.1-0.2 eV. In contrast, range-separated functionals display excellent phosphorescence energies with errors close to 0.05 eV, in this case global-hybrids showing increased discrepancies around 0.5-0.1 eV. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1016/j.jmgm.2023.108460 |
It is part of: | Journal of Molecular Graphics & Modelling, 2023, vol. 122, p. 108460 |
URI: | http://hdl.handle.net/2445/204983 |
Related resource: | https://doi.org/10.1016/j.jmgm.2023.108460 |
ISSN: | 1093-3263 |
Appears in Collections: | Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
260908.pdf | 1.6 MB | Adobe PDF | View/Open Request a copy |
Document embargat fins el 28-3-2025
This item is licensed under a Creative Commons License