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http://hdl.handle.net/2445/206270
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DC Field | Value | Language |
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dc.contributor.author | Monzo Gallo, Patricia | - |
dc.contributor.author | Chumbita, Mariana | - |
dc.contributor.author | Lopera, Carlos | - |
dc.contributor.author | Aiello, Tommaso F. | - |
dc.contributor.author | Peyrony, Oliver | - |
dc.contributor.author | Bodro, Marta | - |
dc.contributor.author | Herrera, Sabina | - |
dc.contributor.author | Sempere, Abiu | - |
dc.contributor.author | Fernández Pittol, Mariana | - |
dc.contributor.author | Cuesta, Genoveva | - |
dc.contributor.author | Simó, Sílvia | - |
dc.contributor.author | Benegas, Mariana | - |
dc.contributor.author | Fortuny, Clàudia | - |
dc.contributor.author | Mensa, Josep | - |
dc.contributor.author | Soriano, Àlex | - |
dc.contributor.author | Puerta Alcalde, Pedro | - |
dc.contributor.author | Marco, Francesc | - |
dc.contributor.author | Garcia Vidal, Carolina | - |
dc.contributor.author | FUNGIclinic group | - |
dc.date.accessioned | 2024-01-24T13:17:04Z | - |
dc.date.available | 2024-03-01T06:10:12Z | - |
dc.date.issued | 2023-03-01 | - |
dc.identifier.issn | 1460-2709 | - |
dc.identifier.uri | http://hdl.handle.net/2445/206270 | - |
dc.description.abstract | We aimed to describe the current epidemiology of both hosts with invasive fungal infections (IFI) and causative fungi. And detail outcomes of these infections at 12 weeks in a real-life cohort of hospitalized patients. The study was retrospective and observational to describe IFI diagnosed in a tertiary hospital (February 2017 - December 2021). We included all consecutive patients meeting criteria for proven or probable IFI according to EORTC-MSG and other criteria. A total of 367 IFI were diagnosed. 11.7% were breakthrough infections, and 56.4% were diagnosed in the intensive care unit (ICU). Corticosteroid use (41.4%) and prior viral infection (31.3%) were the most common risk factors for IFI. Lymphoma and pneumocystis pneumonia were the most common baseline and fungal diseases. Only 12% of IFI occurred in patients with neutropenia. Fungal cultures were the most important diagnostic tests (85.8%). The most frequent IFI were candidemia (42.2%) and invasive aspergillosis (26.7%). Azole-resistant candida strains and non-fumigatus aspergillus infection represented 36.1% and 44.5% of the cases, respectively. Pneumocystosis (16.9%), cryptococcosis (4.6%) and mucormycosis (2.7%) were also frequent, as well as mixed infections (3.4%). Rare fungi accounted for 9.5% of infections. Overall IFI mortality at 12 weeks was 32.2%; higher rates were observed for Mucorales (55.6%), Fusarium (50%) and mixed infections (60%). We documented emerging changes in both hosts and real-life IFI epidemiology. Physicians should be aware of these changes to suspect infections and be aggressive in diagnoses and treatments. Currently, outcomes for such clinical scenarios remain extremely poor.© The Author(s) 2023. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. | ca |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | ca |
dc.publisher | Oxford University Press | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1093/mmy/myad021 | - |
dc.relation.ispartof | Medical Mycology, 2023, vol. 61, num. 3 | - |
dc.relation.uri | https://doi.org/10.1093/mmy/myad021 | - |
dc.rights | (c) Monzo Gallo, Patricia, 2023 | - |
dc.source | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) | - |
dc.subject.classification | Aspergil·losi | - |
dc.subject.classification | Pneumònia | - |
dc.subject.other | Aspergillosis | - |
dc.subject.other | Pneumonia | - |
dc.title | Real-life epidemiology and current outcomes of hospitalized adults with invasive fungal infections | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.date.updated | 2024-01-18T08:31:52Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.idimarina | 9343546 | - |
dc.identifier.pmid | 36861308 | - |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) |
Files in This Item:
File | Description | Size | Format | |
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edited_IFI_VF rev MM_main document.pdf | 284.22 kB | Adobe PDF | View/Open |
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