Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/207574
Title: | Cognitive and Emotional Symptoms Induced by Chronic Stress Are Regulated by EGR1 in a Subpopulation of Hippocampal Pyramidal Neurons. |
Author: | Sancho Balsells, Anna Borràs Pernas, Sara Brito, Verónica Alberch i Vié, Jordi, 1959- Girault, Jean-Antoine Giralt Torroella, Albert |
Keywords: | Hipocamp (Cervell) Neurones Memòria Esquizofrènia Depressió psíquica Estrès (Psicologia) Hippocampus (Brain) Neurons Memory Schizophrenia Mental depression Stress (Psychology) |
Issue Date: | 14-Feb-2023 |
Publisher: | MDPI |
Abstract: | We found that specific manipulation of superficial but not deep pyramidal neurons of the CA1 resulted in the amelioration of depressive-like behaviors and the restoration of cognitive impairments induced by chronic stress. In summary, Egr1 might be a core molecule driving the activation/deactivation of hippocampal neuronal subpopulations underlying stress-induced alterations involving emotional and cognitive sequels. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/ijms24043833 |
It is part of: | International Journal of Molecular Sciences, 2023, vol. 24, num.4 |
URI: | http://hdl.handle.net/2445/207574 |
Related resource: | https://doi.org/10.3390/ijms24043833 |
DOI: | 10.3390/ijms24043833 |
ISSN: | 1661-6596 |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Biomedicina) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
841515.pdf | 2.96 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License