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https://hdl.handle.net/2445/207668
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DC Field | Value | Language |
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dc.contributor.author | Pérez Sisqués, Leticia | - |
dc.contributor.author | Sancho Balsells, Anna | - |
dc.contributor.author | Solana Balaguer, Júlia | - |
dc.contributor.author | Campoy Campos, Genís | - |
dc.contributor.author | Vives Isern, Marcel | - |
dc.contributor.author | Soler Palazón, Ferran | - |
dc.contributor.author | Anglada Huguet, Marta | - |
dc.contributor.author | López Toledano, Miguel Ángel | - |
dc.contributor.author | Mandelkow, Eva Maria | - |
dc.contributor.author | Alberch i Vié, Jordi, 1959- | - |
dc.contributor.author | Giralt Torroella, Albert | - |
dc.contributor.author | Malagelada Grau, Cristina | - |
dc.date.accessioned | 2024-02-16T14:21:57Z | - |
dc.date.available | 2024-02-16T14:21:57Z | - |
dc.date.issued | 2021-06-15 | - |
dc.identifier.issn | 2041-4889 | - |
dc.identifier.uri | https://hdl.handle.net/2445/207668 | - |
dc.description.abstract | We found an unanticipated recovery of several gliosis hallmarks and inflammasome key proteins upon neuronal RTP801 downregulation in the 5xFAD mice. Altogether our results suggest that RTP801 could be a potential future target for theranostic studies since it could be a biomarker of neuroinflammation and neurotoxicity severity of the disease and, at the same time, a promising therapeutic target in the treatment of AD. | - |
dc.format.extent | 13 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isformatof | Reproducció del document publicat a: | - |
dc.relation.ispartof | Cell Death and Disease, 2021, vol. 12, num.6 | - |
dc.rights | cc-by (c) Pérez Sisqués, Leticia et al., 2021 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Biomedicina) | - |
dc.subject.classification | Cervell | - |
dc.subject.classification | Mort cel·lular | - |
dc.subject.classification | Malaltia d'Alzheimer | - |
dc.subject.classification | Malalties cerebrals | - |
dc.subject.classification | Proteïnes | - |
dc.subject.other | Brain | - |
dc.subject.other | Cell death | - |
dc.subject.other | Alzheimer's disease | - |
dc.subject.other | Brain diseases | - |
dc.subject.other | Proteins | - |
dc.title | RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer's disease | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 713034 | - |
dc.date.updated | 2024-02-16T14:21:57Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 34131105 | - |
Appears in Collections: | Articles publicats en revistes (Biomedicina) |
Files in This Item:
File | Description | Size | Format | |
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240384.pdf | 5 MB | Adobe PDF | View/Open |
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