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DC Field | Value | Language |
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dc.contributor.author | Suárez Lledó, Ana | - |
dc.contributor.author | Llop Talaveron, Josep M. | - |
dc.contributor.author | Leiva Badosa, Elisabet | - |
dc.contributor.author | Farran Teixido, Leandre | - |
dc.contributor.author | Miró Martín, Mónica | - |
dc.contributor.author | Bas Minguet, Jordi | - |
dc.contributor.author | Navarro Velázquez, Sergio | - |
dc.contributor.author | Creus Costas, Gloria | - |
dc.contributor.author | Virgili Casas, Nuria | - |
dc.contributor.author | Fernández Álvarez, Mónica | - |
dc.contributor.author | Badía Tahull, María B. | - |
dc.date.accessioned | 2024-02-23T16:03:51Z | - |
dc.date.available | 2024-02-23T16:03:51Z | - |
dc.date.issued | 2023-12-21 | - |
dc.identifier.issn | 2072-6643 | - |
dc.identifier.uri | http://hdl.handle.net/2445/207993 | - |
dc.description.abstract | (Background) Esophagectomy (EPG) presents high morbidity and mortality. Omega-3 fatty acids (omega-3FA) are a pharmaconutrient with benefits for postoperative morbidity. Studies of omega-3FA administered parenterally after esophagectomy are scarce. This study proposes to investigate the effect of combining fish oil lipid emulsions (LE) administered parenterally with enteral nutrition support. (Methods) Randomization was 1:1:1 in three groups: Group A received a LE mixture of 0.4 g/kg/day of fish oil and 0.4 g/kg/day of LCT/MCT 50:50, Group B received 0.8 g/kg/day of fish oil LE, and Group C received 0.8 g/kg/day of LCT/MCT 50:50. Variables were measured at recruitment time and day +1, +3, and +5. Inflammatory variables studied were Interlukin-6, C-reactive protein (CRP), tumoral necrosis factor-alpha (TNF-alpha), IL-10, IL-8 and CD25s. Safety, nutritional parameters and complications were analyzed. (Results) Administration of omega-3LE in the immediate postoperative period did not modulate the earlier inflammatory response. Statistically significant differences were found in IL-6 and CRP overall temporal evolution but were not found when studying the type of LE administered or in patients needing critical care. Administration of omega-3 resulted in safe and improved hypertriglyceridemia, depending on the dose. (Conclusions) omega-3FA has no impact on the early inflammatory postoperative response assessed for a short period but was safe. More studies for longer periods are needed. | - |
dc.format.extent | 12 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI AG | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/nu16010040 | - |
dc.relation.ispartof | Nutrients, 2023, vol. 16, num. 1, p. 40 | - |
dc.relation.uri | https://doi.org/10.3390/nu16010040 | - |
dc.rights | cc by (c) Suárez Lledó, Ana et al, 2023 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Suplements nutritius | - |
dc.subject.classification | Emulsions | - |
dc.subject.other | Dietary supplements | - |
dc.subject.other | Emulsions | - |
dc.title | Effect of Fish Oil Parenteral Emulsion Supplementation on Inflammatory Parameters after Esophagectomy | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2024-01-29T10:22:44Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 38201870 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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nutrients-16-00040-v3.pdf | 675.61 kB | Adobe PDF | View/Open |
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