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Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/208414
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dc.contributor.authorSoriano-Meseguer, Sara-
dc.contributor.authorFuguet i Jordà, Elisabet-
dc.contributor.authorPort, Adriana-
dc.contributor.authorRosés Pascual, Martí-
dc.date.accessioned2024-03-05T18:46:15Z-
dc.date.available2024-03-05T18:46:15Z-
dc.date.issued2023-06-30-
dc.identifier.issn2077-0375-
dc.identifier.urihttp://hdl.handle.net/2445/208414-
dc.description.abstractTwo parallel artificial membrane permeability assay (PAMPA) systems intended for emulating skin permeability have been characterized through the solvation parameter model of Abraham using multilinear regression analysis. The coefficients of the obtained equations have been compared to the ones already established for other PAMPA membranes using statistical tools. The results indicate that both skin membranes are similar to each other in their physicochemical properties. However, they are different from other PAMPA membranes (e.g., intestinal absorption and blood– brain PAMPAs), mainly in terms of hydrophobicity and hydrogen bonding properties. Next, all PAMPA membranes have been compared to relevant biological processes also characterized through the solvation parameter model. The results highlight that skin-PAMPA membranes are a very good choice to emulate skin permeability.-
dc.format.extent12 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherMDPI-
dc.relation.isformatofReproducció del document publicat a: https://doi.org/https://doi.org/10.3390/membranes13070640-
dc.relation.ispartofMembranes, 2023, vol. 13, p. 1-12-
dc.relation.urihttps://doi.org/https://doi.org/10.3390/membranes13070640-
dc.rightscc-by (c) Soriano-Meseguer, S. et al., 2023-
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/-
dc.sourceArticles publicats en revistes (Enginyeria Química i Química Analítica)-
dc.subject.classificationPermeabilitat-
dc.subject.classificationAbsorció intestinal-
dc.subject.classificationSolvatació-
dc.subject.otherPermeability-
dc.subject.otherIntestinal absorption-
dc.subject.otherSolvation-
dc.titleEvaluation of the Ability of PAMPA Membranes to Emulate Biological Processes through the Abraham Solvation Parameter Model-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.identifier.idgrec740911-
dc.date.updated2024-03-05T18:46:15Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
Appears in Collections:Articles publicats en revistes (Institut de Biomedicina (IBUB))
Articles publicats en revistes (Enginyeria Química i Química Analítica)

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