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Title: | Current Approach in the Management of Secondary Immunodeficiency in Patients with Hematological Malignancies: Spanish Expert Consensus Recommendations |
Author: | Boqué, Concepción Sánchez Ramón, Silvia Córdoba, Raúl Moreno, Carol Cabezudo, Elena |
Keywords: | Malalties hematològiques Resposta immunitària Hematologic diseases Immune response |
Issue Date: | 4-Oct-2023 |
Publisher: | MDPI AG |
Abstract: | A Delphi-based survey was designed to assess the opinions of clinical hematologists (n = 17) and clinical immunologists (n = 18) from across Spain on secondary immunodeficiencies (SID) in the management of oncohematological patients. There was 100% agreement on the need to have available guidelines for the management of immunodeficiency in hematological patients; to perform a baseline immunological evaluation in patients with chronic lymphocytic leukemia (CLL), multiple myeloma (MM), lymphoma and hematopoietic stem cell transplantation (HSCT) recipients; and to quantify serum IgG, IgA and IgM levels when SID is suspected. More than 90% agreed on the need for active immunization against seasonal influenza and H1N1, pneumococcus and Haemophilus influenzae. There was a consensus on the monitoring of IgG levels every 3 months (83%) and the need to have available a clinical protocol for the use of IVIG in the management of SID (94%), to monitor trough IgG levels to determine the correct IVIG dose (86%) and to discontinue IVIG after the recovery of IgG levels after 12 months of follow-up (77%). The findings of the present survey may be useful recommendations for hematologists and immunologists to improve the management of SID in daily practice. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/jcm12196356 |
It is part of: | Journal of Clinical Medicine, 2023, vol. 12, num. 19 |
URI: | http://hdl.handle.net/2445/209564 |
Related resource: | https://doi.org/10.3390/jcm12196356 |
ISSN: | 2077-0383 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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