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http://hdl.handle.net/2445/214028
Title: | Repeated pancreatic resection for pancreatic metastases from renal cell Carcinoma: A Spanish multicenter study (PANMEKID) |
Author: | Rojas-holguín, Adela Fondevila-campo, Constantino Sanjuanbenito, Alfonso Fabregat-prous, Joan Secanella-medayo, Luís Rotellar-sastre, Fernando Pardo-sánchez, Fernando Prieto-calvo, Mikel Marín-ortega, Héctor Sánchez-cabús, Santiago Diez-valladares, Luis Alonso-casado, Óscar González-serrano, Carmen Rodríguez-sanjuan, Juan Carlos García-plaza, Gabriel Jaén-torrejimeno, Isabel Suárez-muñoz, Miguel Ángel Becerra-massare, Antonio Rio, Paula Senra-del Pando, Elizabeth López-andújar, Rafael Muñoz-forner, Elena Rodriguez-lópez, Mario Pereira, Fernando Serrablo-requejo, Alejandro Turrión, Víctor Sánchez Garrido, Manuel Jiménez Burdío, Fernando Martín-pérez, Elena Estevan-estevan, Rafael López-guerra, Diego Castell-gómez, José Salinas-gómez, Javier López-baena, José Ángel López-ben, Santiago Solar-garcía, Lorena Pérez-alonso, Alejandro J. Martínez-insfran, Luis Alberto Blas, Juan Luis Cornejo, Marian Gutierrez-calvo, Alberto Pozo, Carlos Domingo-del Ochando-cerdan, Federico Muñoz-bellvís, Luis Rebollar-saenz, José Sánchez, Belinda Jover, José María Gómez-bravo, Miguel Ángel Ramia, José M. Blanco-fernández, Gerardo |
Issue Date: | 1-Feb-2024 |
Publisher: | Elsevier BV |
Abstract: | Background and objectives: Recurrent isolated pancreatic metastasis from Renal Cell Carcinoma (RCC) after pancreatic resection is rare. The purpose of our study is to describe a series of cases of relapse of pancreatic metastasis from renal cancer in the pancreatic remnant and its surgical treatment with a repeated pancreatic resection, and to analyse the results of both overall and disease -free survival. Methods: Multicenter retrospective study of patients undergoing pancreatic resection for RCC pancreatic metastases, from January 2010 to May 2020. Patients were grouped into two groups depending on whether they received a single pancreatic resection (SPS) or iterative pancreatic resection. Data on short and long-term outcome after pancreatic resection were collected. Results: The study included 131 pancreatic resections performed in 116 patients. Thus, iterative pancreatic surgery (IPS) was performed in 15 patients. The mean length of time between the first pancreatic surgery and the second was 48.9 months (95 % CI: 22.2-56.9). There were no differences in the rate of postoperative complications. The DFS rates at 1, 3 and 5 years were 86 %, 78 % and 78 % vs 75 %, 50 % and 37 % in the IPS and SPS group respectively (p = 0.179). OS rates at 1, 3, 5 and 7 years were 100 %, 100 %, 100 % and 75 % in the IPS group vs 95 %, 85 %, 80 % and 68 % in the SPS group (p = 0.895). Conclusion: Repeated pancreatic resection in case of relapse of pancreatic metastasis of RCC in the pancreatic remnant is justified, since it achieves OS results similar to those obtained after the first resection. |
Note: | Reproducció del document publicat a: https://doi.org/10.1016/j.suronc.2024.102039 |
It is part of: | Surgical Oncology, 2024, vol. 52, p. 102039 |
URI: | http://hdl.handle.net/2445/214028 |
Related resource: | https://doi.org/10.1016/j.suronc.2024.102039 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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1-s2.0-S0960740424000070-main.pdf | 1.59 MB | Adobe PDF | View/Open |
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