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https://hdl.handle.net/2445/214527
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DC Field | Value | Language |
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dc.contributor.author | Santoro, Francesco | - |
dc.contributor.author | Núñez Gil, Iván | - |
dc.contributor.author | Viana Llamas, María C. | - |
dc.contributor.author | Alfonso Rodríguez, Emilio | - |
dc.contributor.author | Uribarri, Aitor | - |
dc.contributor.author | Becerra Muñoz, Victor Manuel | - |
dc.contributor.author | Guzman, Gisela Feltes | - |
dc.contributor.author | Di Nunno, Nicola | - |
dc.contributor.author | Lopez Pais, Javier | - |
dc.contributor.author | Cerrato, Enrico | - |
dc.contributor.author | Sinagra, Gianfranco | - |
dc.contributor.author | Mapelli, Massimo | - |
dc.contributor.author | Inciardi, Riccardo M. | - |
dc.contributor.author | Specchia, Claudia | - |
dc.contributor.author | Oriecuia, Chiara | - |
dc.contributor.author | Brunetti, Natale Daniele | - |
dc.date.accessioned | 2024-07-11T14:54:55Z | - |
dc.date.available | 2024-07-11T14:54:55Z | - |
dc.date.issued | 2024-06-01 | - |
dc.identifier.issn | 0953-6205 | - |
dc.identifier.uri | https://hdl.handle.net/2445/214527 | - |
dc.description.abstract | Background: Long-term consequences of COVID-19 are still partly known. Aim of the study: To derive a clinical score for risk prediction of long-term major cardiac adverse events (MACE) and all cause death in COVID-19 hospitalized patients. Methods: 2573 consecutive patients were enrolled in a multicenter, international registry (HOPE-2) from January 2020 to April 2021 and identified as the derivation cohort. Five hundred and twenty-six patients from the CardioCovid-Italy registry were considered as external validation cohort. A long-term prognostic risk score for MACE and all cause death was derived from a multivariable regression model. Results: Out of 2573 patients enrolled in the HOPE-2 registry, 1481 (58 %) were male, with mean age of 60 +/- 16 years. At long-term follow-up, the overall rate of patients affected by MACE and/or all cause death was 7.8 %. After multivariable regression analysis, independent predictors of MACE and all cause death were identified. The HOPE-2 prognostic score was therefore calculated by giving: 1 -4 points for age class ( <65 years, 65 -74, 75 -84, >= 85), 3 points for history of cardiovascular disease, 1 point for hypertension, 3 points for increased troponin serum levels at admission and 2 points for acute renal failure during hospitalization. Score accuracy at ROC curve analysis was 0.79 (0.74 at external validation). Stratification into 3 risk groups ( <3, 3-6, >6 points) classified patients into low, intermediate and high risk. The observed MACE and all-cause death rates were 1.9 %, 9.4 % and 26.3 % for low- intermediate and high-risk patients, respectively (Log-rank test p < 0.01). Conclusions: The HOPE-2 prognostic score may be useful for long-term risk stratification in patients with previous COVID-19 hospitalization. High-risk patients may require a strict follow-up. | - |
dc.format.extent | 7 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier BV | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1016/j.ejim.2024.03.002 | - |
dc.relation.ispartof | European Journal of Internal Medicine, 2024, vol. 124, p. 108-114 | - |
dc.relation.uri | https://doi.org/10.1016/j.ejim.2024.03.002 | - |
dc.rights | cc by (c) Santoro, Francesco et al., 2024 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | COVID-19 | - |
dc.subject.classification | Aturada cardíaca | - |
dc.subject.other | COVID-19 | - |
dc.subject.other | Cardiac arrest | - |
dc.title | Risk prediction of major cardiac adverse events and all-cause death following covid-19 hospitalization at one year follow-up: The HOPE-2 score | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2024-07-11T08:58:39Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 38472045 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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PIIS0953620524000967.pdf | 2.55 MB | Adobe PDF | View/Open |
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