Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/214527
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dc.contributor.authorSantoro, Francesco-
dc.contributor.authorNúñez Gil, Iván-
dc.contributor.authorViana Llamas, María C.-
dc.contributor.authorAlfonso Rodríguez, Emilio-
dc.contributor.authorUribarri, Aitor-
dc.contributor.authorBecerra Muñoz, Victor Manuel-
dc.contributor.authorGuzman, Gisela Feltes-
dc.contributor.authorDi Nunno, Nicola-
dc.contributor.authorLopez Pais, Javier-
dc.contributor.authorCerrato, Enrico-
dc.contributor.authorSinagra, Gianfranco-
dc.contributor.authorMapelli, Massimo-
dc.contributor.authorInciardi, Riccardo M.-
dc.contributor.authorSpecchia, Claudia-
dc.contributor.authorOriecuia, Chiara-
dc.contributor.authorBrunetti, Natale Daniele-
dc.date.accessioned2024-07-11T14:54:55Z-
dc.date.available2024-07-11T14:54:55Z-
dc.date.issued2024-06-01-
dc.identifier.issn0953-6205-
dc.identifier.urihttps://hdl.handle.net/2445/214527-
dc.description.abstractBackground: Long-term consequences of COVID-19 are still partly known. Aim of the study: To derive a clinical score for risk prediction of long-term major cardiac adverse events (MACE) and all cause death in COVID-19 hospitalized patients. Methods: 2573 consecutive patients were enrolled in a multicenter, international registry (HOPE-2) from January 2020 to April 2021 and identified as the derivation cohort. Five hundred and twenty-six patients from the CardioCovid-Italy registry were considered as external validation cohort. A long-term prognostic risk score for MACE and all cause death was derived from a multivariable regression model. Results: Out of 2573 patients enrolled in the HOPE-2 registry, 1481 (58 %) were male, with mean age of 60 +/- 16 years. At long-term follow-up, the overall rate of patients affected by MACE and/or all cause death was 7.8 %. After multivariable regression analysis, independent predictors of MACE and all cause death were identified. The HOPE-2 prognostic score was therefore calculated by giving: 1 -4 points for age class ( <65 years, 65 -74, 75 -84, >= 85), 3 points for history of cardiovascular disease, 1 point for hypertension, 3 points for increased troponin serum levels at admission and 2 points for acute renal failure during hospitalization. Score accuracy at ROC curve analysis was 0.79 (0.74 at external validation). Stratification into 3 risk groups ( <3, 3-6, >6 points) classified patients into low, intermediate and high risk. The observed MACE and all-cause death rates were 1.9 %, 9.4 % and 26.3 % for low- intermediate and high-risk patients, respectively (Log-rank test p < 0.01). Conclusions: The HOPE-2 prognostic score may be useful for long-term risk stratification in patients with previous COVID-19 hospitalization. High-risk patients may require a strict follow-up.-
dc.format.extent7 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherElsevier BV-
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1016/j.ejim.2024.03.002-
dc.relation.ispartofEuropean Journal of Internal Medicine, 2024, vol. 124, p. 108-114-
dc.relation.urihttps://doi.org/10.1016/j.ejim.2024.03.002-
dc.rightscc by (c) Santoro, Francesco et al., 2024-
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.sourceArticles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))-
dc.subject.classificationCOVID-19-
dc.subject.classificationAturada cardíaca-
dc.subject.otherCOVID-19-
dc.subject.otherCardiac arrest-
dc.titleRisk prediction of major cardiac adverse events and all-cause death following covid-19 hospitalization at one year follow-up: The HOPE-2 score-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.date.updated2024-07-11T08:58:39Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
dc.identifier.pmid38472045-
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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