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https://hdl.handle.net/2445/220012
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DC Field | Value | Language |
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dc.contributor.author | Selvitella, Silvia | - |
dc.contributor.author | Franco, Marta Pérez | - |
dc.contributor.author | Aran, Begoña | - |
dc.contributor.author | Veiga, Anna | - |
dc.contributor.author | Kuebler, Bernd | - |
dc.date.accessioned | 2025-03-25T15:07:36Z | - |
dc.date.available | 2025-03-25T15:07:36Z | - |
dc.date.issued | 2024-12-01 | - |
dc.identifier.issn | 1876-7753 | - |
dc.identifier.uri | https://hdl.handle.net/2445/220012 | - |
dc.description.abstract | mRNA reprogramming is a technology for generating iPSCs with high efficiency and safety. However, it is not suitable for reprogramming non-adherent cells, the primary cell type in blood. An alternative is to obtain adherent cells from blood for this technology. To validate this approach, we generated a human iPSC line from blood outgrowth endothelial cells (BOECs) using mRNA-based reprogramming. The resulting line, CTRL EiPS J9 mR6F-8, meets iPSC criteria, including an undifferentiated state, pluripotency, genome integrity. This line is available upon request. | - |
dc.format.extent | 5 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier BV | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1016/j.scr.2024.103606 | - |
dc.relation.ispartof | Stem Cell Research, 2024, vol. 81 | - |
dc.relation.uri | https://doi.org/10.1016/j.scr.2024.103606 | - |
dc.rights | cc-by (c) Selvitella, Silvia et al., 2024 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Enginyeria genètica | - |
dc.subject.classification | Endoteli | - |
dc.subject.classification | Cèl·lules | - |
dc.subject.other | Genetic engineering | - |
dc.subject.other | Endothelium | - |
dc.subject.other | Cells | - |
dc.title | Generation of the CTRL EiPS J9 mR6F-8 iPSC line derived from healthy human outgrowth blood endothelial cells (BOECs) using mRNA reprogramming methodology | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2024-12-10T10:35:35Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 39541769 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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1-s2.0-S1873506124003040-main.pdf | 5.48 MB | Adobe PDF | View/Open |
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