Please use this identifier to cite or link to this item:
https://hdl.handle.net/2445/221673
Title: | Economic burden of secondary progressive multiple sclerosis: DISCOVER study |
Author: | Oreja-Guevara, Celia Meca Lallana, José E. Gomez-estevez, Irene Ara Callizo, José Ramón Hernández Pérez, Miguel Ángel Gracia Gil, Julia Alonso Torres, Ana María Pilo De La Fuente, Belén Ramio Torrentà, Lluís Eichau Madueño, Sara Gascón Gimenez, Francisco Casanova, Bonaventura Martínez Yélamos, Sergio Aguado Valcarcel, Marta Martínez Ginés, María Luisa El Berdei Montero, Yasmina López Real, Ana María González Quintanilla, Vicente López de Silanes, Carlos Martínez Rodríguez, José Enrique Costa Frossard, Lucienne Garcés Redondo, Moises Labiano Fontcuberta, Andrés Castellanos Pinedo, Fernando García Merino, Juan Antonio Muñoz Fernández, Carmen Castillo Triviño, Tamara Meca Lallana, Virginia Peña Martínez, Joaquín Rodríguez Antiguedad, Alfredo Prieto González, José María Agueera Morales, Eduardo Pérez Molina, Inmaculada Solar Sánchez, Dulce M. Herrera Varo, Nicolás Aguirre Vázquez, Marta Rodríguez Barrios, José Manuel Río, Jordi |
Keywords: | Esclerosi múltiple Cost de l'assistència sanitària Cost Multiple sclerosis Cost of medical care Cost |
Issue Date: | 10-Apr-2025 |
Publisher: | Springer Science and Business Media LLC |
Abstract: | BackgroundTo estimate the socioeconomic burden of people with secondary progressive multiple sclerosis (pwSPMS), considering direct health care, direct non-health care, and indirect costs, and to evaluate the relationship between costs and patients' functional outcomes.MethodsObservational, cross-sectional, multicenter study with retrospective real-life clinical practice data collection from pwSPMS visiting the neurology services of 34 hospitals during 2019-2020. Clinical data included Expanded Disability Status Scale scores, number of relapses, magnetic resonance imaging, disease-modifying treatment (DMT), symptoms, and comorbidities from 24 months before the study visit. Resource use and allied costs were collected 12 months before the study visit. Patient-reported outcomes, functional and cognitive scales were also collected.Results70% of pwSPMS used primary care services, and nearly 50% needed assistance in a daycare or rehabilitation center. Almost 60% of the participants were receiving DMT at the study visit, and 80% needed support for domestic/housekeeping tasks. More than 90% were inactive at work, with nearly 80% taking early retirement. The estimated total annual cost per pwSPMS in Spain was almost 41,500, of which more than 50% (21,400) were indirect costs, followed by direct health care costs (30%, 11,300), and, finally, direct non-health care costs (about 20%, 8,800). Older patients with severe disabilities and worse functional outcomes incurred higher costs.ConclusionsSPMS is a major burden on health care systems, patients, and society as a whole. Health care and societal policies should be aimed at improving the SPMS care pathway and minimizing patients' funding of direct non-health care costs.Trial registrationThe trial is a non-interventional study. The NCC code is CBAF312AES01/NOV-EMS-2019-01. |
Note: | Reproducció del document publicat a: https://doi.org/10.1186/s12913-025-12592-1 |
It is part of: | BMC Health Services Research, 2025, vol. 25 |
URI: | https://hdl.handle.net/2445/221673 |
Related resource: | https://doi.org/10.1186/s12913-025-12592-1 |
ISSN: | 1472-6963 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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