Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/221684
Title: Microbiome as a predictive biomarker in locally advanced rectal cancer
Author: Mulet Margalef, Núria
Martín Abad, Berta
Martínez Balibrea, Eva
Manzano Mozo, José Luís
Borgognone, Alessandra
Obón Santacana, Mireia
Keywords: Càncer colorectal
Microbiota intestinal
Colorectal cancer
Gastrointestinal microbiome
Issue Date: 24-Mar-2025
Publisher: OAE Publishing Inc.
Abstract: The incidence of locally advanced rectal cancer (LARC) among young people is rising alarmingly. In recent years, new protocols have been introduced for the management of LARC, some of which are associated with the risk of significant toxicity. Despite these advancements, robust predictive biomarkers for LARC have yet to be established. The microbiome has emerged as a potential biomarker due to its interaction with tumor multiomics. This article provides a critical overview of the current evidence on the microbiome and LARC, including its relationship with the immune system and epigenomics, and also highlights both the current limitations and future perspectives in the field.
Note: Reproducció del document publicat a: https://doi.org/10.20517/mrr.2024.85
It is part of: Microbiome Research Reports, 2025, vol. 4, num. 2
URI: https://hdl.handle.net/2445/221684
Related resource: https://doi.org/10.20517/mrr.2024.85
ISSN: 2771-5965
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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