| Title: | Metachronous colorectal cancer risks after extended or segmental resection in MLH1, MSH2, and MSH6 Lynch syndrome: multicentre study from the Prospective Lynch Syndrome Database |
| Author: | Prospective Lynch Syndrome Database
Zalevskaja, K
Ojala, K
Petrov, A
Haupt, S
Sunde, L
Bernstein, I
A Jenkins, M
Aretz, S
Nielsen, M
Capella, G
Balaguer, F
G Evans, D
Burn, J
Holinski-feder, E
Bertario, L
Bonanni, B
Lindblom, A
Levi, Z
Macrae, F
Winship, I
Plazzer, J-p
Sijmons, R
Laghi, L
Della Valle, A
Heinimann, K
Dębniak, T
Fruscio, R
Lopez-koestner, F
Alvarez-valenzuela, K
H Katz, L
Laish, I
Vainer, E
Vaccaro, C
M Carraro, D
Monahan, K
Half, E
Stakelum, A
Winter, D
Kennelly, R
Gluck, N
Sheth, H
Abu-freha, N
Greenblatt, M
M Rossi, B
Bohorquez, M
M Cavestro, G
S Lino-silva, L
Horisberger, K
G Tibiletti, M
Do Nascimento, I
Thomas, H
T Rossi, N
A Da Silva, L
Zaránd, A
Ruiz-bañobre, J
Heuveline, V
J Lindberg, L
Gögenur, I
L Hopper, J
K Win, A
W Haile, R
Lindor, N
Gallinger, S
Le Marchand, L
A Newcomb, P
Figueiredo, J
D Buchanan, D
N Thibodeau, S
V Knebel Doeberitz, M
Loeffler, M
Rahner, N
Schröck, E
Steinke-lange, V
Schmiegel, W
Vangala, D
Perne, C
Hüneburg, R
Redler, S
Büttner, R
Weitz, J
Pineda, M
Duenas, N
Brunet Vidal, J
Moreira, L
Sánchez, A
Castillo-iturra, J
Hovig, E
Green, K
Lalloo, F
Hill, J
Crosbie, E
Mints, M
Goldberg, Y
Tjandra, D
W Ten Broeke, S
Kariv, R
Rosner, G
Jain, A
Shah, P |
| Issue Date: | 28-Mar-2025 |
| Publisher: | Oxford University Press (OUP) |
| Abstract: | This first prospective observational study evaluates the impact of extended versus segmental colorectal surgery on the risk of metachronous colorectal cancer (CRC) in patients with Lynch syndrome, analyzing data from the Prospective Lynch Syndrome Database version 5. Extended resection significantly reduced the risk of metachronous CRC in path_MLH1, path_MSH2, and path_MSH6 carriers compared to segmental resection. |
| Note: | Reproducció del document publicat a: https://doi.org/10.1093/bjs/znaf061 |
| It is part of: | British journal of surgery, 2025, vol. 112, issue. 4 |
| URI: | https://hdl.handle.net/2445/222101 |
| Related resource: | https://doi.org/10.1093/bjs/znaf061 |
| Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
|
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