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https://hdl.handle.net/2445/222655
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DC Field | Value | Language |
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dc.contributor.author | Sans de San Nicolàs, Lídia | - |
dc.contributor.author | Czarnowicki, Tali | - |
dc.contributor.author | Akdis, Mubeccel | - |
dc.contributor.author | Pujol, Ramon M. | - |
dc.contributor.author | Lozano-Ojalvo, Daniel | - |
dc.contributor.author | Leung, Donald Y. M. | - |
dc.contributor.author | Guttman-Yassky, Emma | - |
dc.contributor.author | Santamaria Babí, Luis F. | - |
dc.date.accessioned | 2025-07-29T10:08:23Z | - |
dc.date.available | 2025-07-29T10:08:23Z | - |
dc.date.issued | 2023-07-13 | - |
dc.identifier.issn | 0105-4538 | - |
dc.identifier.uri | https://hdl.handle.net/2445/222655 | - |
dc.description.abstract | Circulating skin-homing cutaneous lymphocyte-associated antigen (CLA)+ T cells constitute a small subset of human memory T cells involved in several aspects of atopic dermatitis: Staphylococcus aureus related mechanisms, the abnormal Th2 immune response, biomarkers, clinical aspects of the patients, pruritus, and the mechanism of action of targeted therapies. Superantigens, IL-13, IL-31, pruritus, CCL17 and early effects on dupilumab-treated patients have in common that they are associated with the CLA+ T cell mechanisms in atopic dermatitis patients. The function of CLA+ T cells corresponds with the role of T cells belonging to the skin-associated lymphoid tissue and could be a reason why they reflect different mechanisms of atopic dermatitis and many other T cell mediated skin diseases. The goal of this review is to gather all this translational information of atopic dermatitis pathology. | - |
dc.format.extent | 11 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | John Wiley & Sons | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1111/all.15816 | - |
dc.relation.ispartof | Allergy, 2024, vol. 79, num.1, p. 15-25 | - |
dc.relation.uri | https://doi.org/10.1111/all.15816 | - |
dc.rights | cc by-nc 4.0 (c) Sans-de San Nicolàs, L., et al., 2024 | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.source | Articles publicats en revistes (Biologia Cel·lular, Fisiologia i Immunologia) | - |
dc.subject.classification | Marcadors bioquímics | - |
dc.subject.classification | Dermatitis atòpica | - |
dc.subject.classification | Cèl·lules T | - |
dc.subject.other | Biochemical markers | - |
dc.subject.other | Atopic dermatitis | - |
dc.subject.other | T cells | - |
dc.title | CLA+ memory T cells in atopic dermatitis CLA plus T cells and atopic dermatitis | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 743209 | - |
dc.date.updated | 2025-07-29T10:08:23Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Biologia Cel·lular, Fisiologia i Immunologia) |
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File | Description | Size | Format | |
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844055.pdf | 1.75 MB | Adobe PDF | View/Open |
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