Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/222834
Title: Neurologists’ Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants
Author: Monreal, Enric
Gómez Ballesteros, Rocío
Meca Lallana, Virginia
Caminero, Ana
Meca Lallana, José E.
Martínez Yélamos, Sergio
Landete, Lamberto
García Domínguez, José M.
Agüera, Eduardo
García Arcelay, Elena
Medrano, Nicolas
Villar, Luisa M.
Maurino, Jorge
Keywords: Esclerosi múltiple
Medicina basada en l'evidència
Multiple sclerosis
Evidence-based medicine
Issue Date: 1-Jul-2025
Publisher: Informa UK Limited
Abstract: Purpose: Integration of evidence-based innovations, such as serum neurofilament light chain (sNfL) measurement into routine practice represents a pivotal opportunity to advance personalized care in multiple sclerosis (MS) management. This study assessed neurologists' openness to adopting healthcare innovations (sNfL testing), focusing on individual characteristics and structural factors like workplace environment and resources. Methods: An observational, cross-sectional study was conducted in partnership with the Spanish Society of Neurology. Neurologists caring for patients with MS completed an e-survey assessing openness to innovation using the Openness subscale of the EvidenceBased Practice Attitude Scale (EBPAS), alongside measures of empathy, healthcare-related regret, risk preferences, burnout, and workplace communication. Logistic and linear regression models were conducted to identify predictors of openness to innovation. Results: One hundred and sixteen neurologists were studied. Mean age (SD) was 41.9 (10.1) years, 53.4% were male. Mean experience as neurologists was 16.0 (9.2) years and 96.6% worked in an academic hospital. Median (IQR) EBPAS-Openness score was 3.0 (2.5-3.5), with 54.3% (n=63) of participants demonstrating openness to innovation. Participants fully dedicated to MS care, managing higher patient volumes, engaged in research publications, with access to serum neurofilament light chain testing, and a greater propensity for risk-taking, were more open to adopting innovations than their counterparts. Multivariate logistic regression analysis showed that access to sNfL testing and higher empathy levels were significant predictors of openness (OR=3.52, CI 95%: 1.3-10.3; p=0.016 and OR=1.09, CI 95%: 1.0-1.2; p=0.005, respectively). Complementary linear regression reinforced the significant positive association between higher EBPAS-Openness scores and empathy (estimate=0.024, p=0.001). Conclusion: Neurologists exhibited a varied openness to innovation. Implementing initial innovative strategies in clinical practice should prioritize neurologists with specific profiles to support the integration of emerging tools and personalized healthcare approaches in MS care.
Note: Reproducció del document publicat a: https://doi.org/10.2147/NDT.S524459
It is part of: Neuropsychiatric Disease and Treatment, 2025, vol. 21, p. 1523-1531
URI: https://hdl.handle.net/2445/222834
Related resource: https://doi.org/10.2147/NDT.S524459
ISSN: 1178-2021
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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