Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/222902
Title: A Review of the Status of Brain Structure Research in Transsexualism
Author: Guillamon Fernández, Antonio
Junqué i Plaja, Carme, 1955-
Gómez Gil, Esther
Keywords: Transsexualitat
Diferències entre sexes
Transsexualism
Sex differences
Issue Date: 2-Jun-2016
Publisher: Springer Verlag
Abstract: The present review focuses on the brain structure of male-to-female (MtF) and female-to-male (FtM) homosexual transsexuals before and after cross-sex hormone treatment as shown by in vivo neuroimaging techniques. Cortical thickness and diffusion tensor imaging studies suggest that the brain of MtFs presents complex mixtures of masculine, feminine, and demasculinized regions, while FtMs show feminine, masculine, and defeminized regions. Consequently, the specific brain phenotypes proposed for MtFs and FtMs differ from those of both heterosexual males and females. These phenotypes have theoretical implications for brain intersexuality, asymmetry, and body perception in transsexuals as well as for Blanchard's hypothesis on sexual orientation in homosexual MtFs. Falling within the aegis of the neurohormonal theory of sex differences, we hypothesize that cortical differences between homosexual MtFs and FtMs and male and female controls are due to differently timed cortical thinning in different regions for each group. Cross-sex hormone studies have reported marked effects of the treatment on MtF and FtM brains. Their results are used to discuss the early postmortem histological studies of the MtF brain.   
Note: Reproducció del document publicat a: https://doi.org/10.1007/s10508-016-0768-5
It is part of: Archives of Sexual Behavior, 2016, vol. 45, num.7, p. 1615-1648
URI: https://hdl.handle.net/2445/222902
Related resource: https://doi.org/10.1007/s10508-016-0768-5
ISSN: 0004-0002
Appears in Collections:Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

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