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https://hdl.handle.net/2445/223249| Title: | Modelling Nanoparticle-Cell Interactions: A Kinetic Approach |
| Author: | Román Pobo, Claudia |
| Director/Tutor: | Miguel López, María del Carmen Basile, Marco Xie, Zhendong |
| Keywords: | Biofísica Cinètica d'unió Treballs de fi de grau Biophysics Binding kinetics Bachelor's theses |
| Issue Date: | Jun-2025 |
| Abstract: | This project addresses the effect of nanoparticle functionalisation on binding affinity to endothelial brain cells. This kind of characterization is fundamental to the optimization of drug delivery to the brain, allowing for treatment of neurodegenerative diseases. For this, we perform a proof of concept binding experiment on bEnd.3 cells with ApoE-functionalized and pristine PEG-PLA polymersomes, and propose a deterministic kinetic model to describe these systems. |
| Note: | Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2025, Tutors: Maria del Carmen Miguel López, Marco Basile, Zhendong Xie |
| URI: | https://hdl.handle.net/2445/223249 |
| Appears in Collections: | Treballs Finals de Grau (TFG) - Física |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| TFG_Román_Pobo_Claudia.pdf | 776.22 kB | Adobe PDF | View/Open |
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