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Title: Systemic lupus erythematosus in the elderly: Clinical and immunological characteristics.
Author: Font Franco, Josep, 1953-2006
Pallarés Ferreres, Lucio
Cervera i Segura, Ricard, 1960-
López-Soto, Alfonso
Navarro López, Margarita
Bosch Aparici, Francisco Javier
Ingelmo Morín, Miguel
Keywords: Lupus eritematós
Malalties de les persones grans
Lupus erythematosus
Older people diseases
Issue Date: 1991
Publisher: BMJ Group
Abstract: Systemic lupus erythematosus (SLE) predominantly affects young women in their 20s. In 40 out of 250 (16%) patients with SLE seen in our hospital disease onset occurred after the age of 50. The interval between the time of onset and diagnosis was five years in this older group compared with three years in the younger group. Arthritis, as a first symptom, was less common in the older onset group. During the follow up a lower incidence of arthritis, malar rash, photosensitivity, and nephropathy was found in the older onset group. In contrast, this group showed an increased incidence of myositis. High titres of anti-dsDNA tended to occur less often and the incidence of anti-Ro antibodies was lower in the older onset group. These features seem to distinguish patients with older onset SLE as a particular subset.
Note: Reproducció digital del document publicat a:
It is part of: Annals of the Rheumatic Diseases, 1991, vol. 50, núm. 10, p. 702-705
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ISSN: 0003-4967
Appears in Collections:Articles publicats en revistes (Medicina)

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