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|Knock, knock, knocking on muscle doors. Visions on the transport of substrates across the plasma membrane in muscle.
|Zorzano Olarte, Antonio
Fandos Espallargas, César
Palacín Prieto, Manuel
|Institut d'Estudis Catalans
|Muscle is a major player in metabolism. It uses large amounts of glucose in the absorptive state and changes in muscle insulin-stimulated glucose uptake alter whole-body glucose disposal. Lipid substrates such as fatty acids or ketone bodies are preferentially used by muscle in certain physiological conditions. Muscle is also the main reservoir of amino acids and protein. The activity of many different plasma membrane transporters such as glucose carriers, carnitine, creatine or amino acid transporters maintain muscle metabolism by taking up or releasing substrates or metabolites across the cell surface. The goal of this review is the molecular characterization of muscle membrane transporter proteins and the analysis of their regulatory roles.
|Reproducció del document publicat a: http://www.raco.cat/index.php/Contributions/article/view/157673/209564
|It is part of:
|Contributions to Science, 2001, vol. 1, num. 3, p. 267-298
|Appears in Collections:
|Articles publicats en revistes (Bioquímica i Biomedicina Molecular)
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