1. Dipòsit Digital de la Universitat de Barcelona
  2. Recerca
  3. Ciències Fisiològiques
  4. Articles publicats en revistes (Ciències Fisiològiques)
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/34526
Full metadata record
DC FieldValueLanguage
dc.contributor.authorKurdián, Melania-
dc.contributor.authorHerrero Fresneda, Immaculada-
dc.contributor.authorLloberas Blanch, Núria-
dc.contributor.authorGiménez Bonafé, Pepita-
dc.contributor.authorCoria, Virginia-
dc.contributor.authorGrande, María T.-
dc.contributor.authorBoggia, José-
dc.contributor.authorMalacrida, Leonel-
dc.contributor.authorTorras Ambròs, Joan-
dc.contributor.authorArévalo, Miguel A.-
dc.contributor.authorGonzález-Martínez, Francisco-
dc.contributor.authorLópez-Novoa, José M.-
dc.contributor.authorGrinyó Boira, Josep M.-
dc.contributor.authorNoboa, Oscar-
dc.date.accessioned2013-04-11T11:31:24Z-
dc.date.available2013-04-11T11:31:24Z-
dc.date.issued2012-03-12-
dc.identifier.issn1932-6203-
dc.identifier.urihttps://hdl.handle.net/2445/34526-
dc.description.abstractThe immunosuppressive mammalian target of rapamycin (mTOR) inhibitors are widely used in solid organ transplantation, but their effect on kidney disease progression is controversial. mTOR has emerged as one of the main pathways regulating cell growth, proliferation, differentiation, migration, and survival. The aim of this study was to analyze the effects of delayed inhibition of mTOR pathway with low dose of everolimus on progression of renal disease and TGFβ expression in the 5/6 nephrectomy model in Wistar rats.-
dc.format.extent9 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoengeng
dc.publisherPublic Library of Science (PLoS)-
dc.relation.isformatofReproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0032516-
dc.relation.ispartofPLoS One, 2012, vol. 7, núm. 3, p. e32516-
dc.relation.urihttp://dx.doi.org/10.1371/journal.pone.0032516-
dc.rightscc-by (c) Kurdián et al., 2012-
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es-
dc.sourceArticles publicats en revistes (Ciències Fisiològiques)-
dc.subject.classificationMedicamentscat
dc.subject.classificationTransplantament renalcat
dc.subject.classificationProteïnúriacat
dc.subject.classificationImmunosupressiócat
dc.subject.otherDrugseng
dc.subject.otherKidney transplantationeng
dc.subject.otherProteinuriaeng
dc.subject.otherImmunosuppressioneng
dc.titleDelayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction modeleng
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.identifier.idgrec606624-
dc.date.updated2013-04-11T11:31:24Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
dc.identifier.pmid22427849-
Appears in Collections:Articles publicats en revistes (Ciències Fisiològiques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Files in This Item:
File Description SizeFormat 
606624.pdf650.73 kBAdobe PDFView/Open
Show simple item record


This item is licensed under a Creative Commons License Creative Commons