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Title: An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines
Author: Amat Tusón, Mercedes
Pérez Bosch, Maria
Minaglia, Annamaria Tania
Bosch Cartes, Joan
Keywords: Compostos organometàl·lics
Síntesi orgànica
Organometallic compounds
Synthetic organic chemistry
Issue Date: 13-Jun-2008
Publisher: American Chemical Society
Abstract: A synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position.
Note: Versió postprint del document publicat a:
It is part of: Journal of Organic Chemistry, 2008, vol. 73, num. 17, p. 6920-6923
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ISSN: 0022-3263
Appears in Collections:Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

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