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http://hdl.handle.net/2445/36346| Title: | An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines |
| Author: | Amat Tusón, Mercedes Pérez Bosch, Maria Minaglia, Annamaria Tania Bosch Cartes, Joan |
| Keywords: | Compostos organometàl·lics Coure Síntesi orgànica Lactames Organometallic compounds Copper Synthetic organic chemistry Lactams |
| Issue Date: | 13-Jun-2008 |
| Publisher: | American Chemical Society |
| Abstract: | A synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position. |
| Note: | Versió postprint del document publicat a: http://dx.doi.org/10.1021/jo801172b |
| It is part of: | Journal of Organic Chemistry, 2008, vol. 73, num. 17, p. 6920-6923 |
| URI: | http://hdl.handle.net/2445/36346 |
| Related resource: | http://dx.doi.org/10.1021/jo801172b |
| ISSN: | 0022-3263 |
| Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 559907.pdf | 232.19 kB | Adobe PDF | View/Open |
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