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Title: Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.
Author: Rodríguez García, Marta
Climent, Núria
Oliva, Harold
Casanova Güell, Víctor
Franco Fernández, Rafael
León García, Agathe
Gatell, José M.
García, Felipe
Gallart, Teresa
Keywords: VIH (Virus)
HIV (Viruses)
Issue Date: 2010
Publisher: Public Library of Science (PLoS)
Abstract: Defensins are natural endogenous antimicrobial peptides with potent anti-HIV activity and immuno-modulatory effects. We recently demonstrated that immature dendritic cells (DC) produce α-defensins1-3 and that α-defensins1-3 modulate DC generation and maturation. Since DC-HIV interaction plays a critical role during the first steps of HIV infection, we investigated the possible impact of α-defensins1-3 production by DC on disease progression.
Note: Reproducció del document publicat a:
It is part of: PLoS One, 2010, vol. 5, num. 2, p. e9436-e9436
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ISSN: 1932-6203
Appears in Collections:Articles publicats en revistes (Bioquímica i Biomedicina Molecular)
Articles publicats en revistes (Medicina)

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